Evidence map›Paper›PMID 26850978›Full record

ArticleNeurology2016

Incontinence and gait disturbance after intraventricular extension of intracerebral hemorrhage.

Daniel Woo, Andrew J Kruger, Padmini Sekar, Mary Haverbusch, Jennifer Osborne, Charles J Moomaw, Sharyl Martini, Shahla M Hosseini, Simona Ferioli, Bradford B Worrall and 8 more

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Daniel WooFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL. woodl@ucmail.uc.edu.
Andrew J KrugerFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Padmini SekarFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Mary HaverbuschFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Jennifer OsborneFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Charles J MoomawFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Sharyl MartiniFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Shahla M HosseiniFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Simona FerioliFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Bradford B WorrallFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Mitchell S V ElkindFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Gene SungFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Michael L JamesFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Fernando D TestaiFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Carl D LangefeldFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Joseph P BroderickFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Sebastian KochFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
Matthew L FlahertyFrom the Department of Neurology and Rehabilitation Medicine (D.W., A.J.K., P.S., M.H., J.O., C.J.M., S.M.H., S.F., J.P.B., M.L.F.), University of Cincinnati College of Medicine, OH; Department of Neurology (S.M.), Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX; Departments of Neurology and Public Health Sciences (B.B.W.), University of Virginia School of Medicine, Charlottesville; Department of Neurology (M.S.V.E.), College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; Department of Neurology (G.S.), University of Southern California, Los Angeles; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Departments of Neurology and Rehabilitation (F.D.T.), University of Illinois at Chicago; Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L.), Wake Forest School of Medicine, Winston-Salem, NC; and Miller School of Medicine (S.K.), University of Miami, FL.
University of Illinois Chicago · USUniversity of Southern California · USDuke University · USColumbia University · USUniversity of Virginia · USBaylor College of Medicine · USMichael E. DeBakey VA Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
Genetic&Environment Risk Factors for Hemorrhagic StrokeR01NS036695 · NINDS · UNIVERSITY OF CINCINNATI · PI WOO, DANIEL · 1997 to 2012
$14.1M
Genetic and Environmental Risk Factors for Hemorrhagic StrokeU01NS036695 · NINDS · UNIVERSITY OF CINCINNATI · PI ROSAND, JONATHAN, WOO, DANIEL · 2016 to 2020
$7.0M
NCATS NIH HHS UL1 TR001425NINDS NIH HHS R01NS036695NINDS NIH HHS U01 NS036695NINDS NIH HHS U01 NS069763NINDS NIH HHS U01NS069763
6 · The paper itself

Abstract

objectiveWe tested the hypothesis that intraventricular hemorrhage (IVH) is associated with incontinence and gait disturbance among survivors of intracerebral hemorrhage (ICH) at 3-month follow-ups.

methodsThe Genetic and Environmental Risk Factors for Hemorrhagic Stroke study was used as the discovery set. The Ethnic/Racial Variations of Intracerebral Hemorrhage study served as a replication set. Both studies performed prospective hot-pursuit recruitment of ICH cases with 3-month follow-up. Multivariable logistic regression analyses were computed to identify risk factors for incontinence and gait dysmobility at 3 months after ICH.

resultsThe study population consisted of 307 ICH cases in the discovery set and 1,374 cases in the replication set. In the discovery set, we found that increasing IVH volume was associated with incontinence (odds ratio [OR] 1.50; 95% confidence interval [CI] 1.10-2.06) and dysmobility (OR 1.58; 95% CI 1.17-2.15) after controlling for ICH location, initial ICH volume, age, baseline modified Rankin Scale score, sex, and admission Glasgow Coma Scale score. In the replication set, increasing IVH volume was also associated with both incontinence (OR 1.42; 95% CI 1.27-1.60) and dysmobility (OR 1.40; 95% CI 1.24-1.57) after controlling for the same variables.

conclusionICH subjects with IVH extension are at an increased risk for developing incontinence and dysmobility after controlling for factors associated with severity and disability. This finding suggests a potential target to prevent or treat long-term disability after ICH with IVH.

Indexed as

AgedAged, 80 and overCase-Control StudiesCerebral HemorrhageCerebral VentriclesCohort StudiesFemaleFollow-Up StudiesGait Disorders, NeurologicHumansMaleMiddle AgedProspective StudiesTreatment OutcomeUrinary Incontinence

Identifiers

PMID26850978
PMCPMC4782110
OpenAlexW2314732469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.