Evidence map›Paper›PMID 26849891›Full record

Observational studyRheumatology international2016

Mapping health assessment questionnaire disability index (HAQ-DI) score, pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) onto the EuroQol-5D (EQ-5D) utility score with the KORean Observational study Network for Arthritis (KORONA) registry data.

Hye-Lin Kim, Dam Kim, Eun Jin Jang, Min-Young Lee, Hyun Jin Song, Sun-Young Park, Soo-Kyung Cho, Yoon-Kyoung Sung, Chan-Bum Choi, Soyoung Won and 22 more

Abstract readComparative StudyMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Rheumatology international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Hye-Lin KimSchool of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-Gu, Suwon, Gyeonggi-do, 440-746, Republic of Korea.
Dam KimDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Eun Jin JangDepartment of Information Statistics, Andong National University, Andong, Republic of Korea.
Min-Young LeeSchool of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-Gu, Suwon, Gyeonggi-do, 440-746, Republic of Korea.
Hyun Jin SongSchool of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-Gu, Suwon, Gyeonggi-do, 440-746, Republic of Korea.
Sun-Young ParkSchool of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-Gu, Suwon, Gyeonggi-do, 440-746, Republic of Korea.
Soo-Kyung ChoDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Yoon-Kyoung SungDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Chan-Bum ChoiDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Soyoung WonClinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, Republic of Korea.
So-Young BangHanyang University Guri Hospital, Guri, Republic of Korea.
Hoon-Suk ChaSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Jung-Yoon ChoeCatholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Won Tae ChungDong-A University Hospital, Busan, Republic of Korea.
Seung-Jae HongKyung Hee University Hospital, Seoul, Republic of Korea.
Jae-Bum JunDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Jinseok KimJeju National University Hospital, Jeju, Republic of Korea.
Seong-Kyu KimCatholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Tae-Hwan KimDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Tae-Jong KimChonnam National University Hospital, Gwangju, Republic of Korea.
Eunmi KohSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Hwajeong LeeCatholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Hye-Soon LeeHanyang University Guri Hospital, Guri, Republic of Korea.
Jisoo LeeEwha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Shin-Seok LeeChonnam National University Hospital, Gwangju, Republic of Korea.
Sung Won LeeDong-A University Hospital, Busan, Republic of Korea.
Sung-Hoon ParkCatholic University of Daegu School of Medicine, Daegu, Republic of Korea.
Seung-Cheol ShimChungnam National University Hospital, Daejeon, Republic of Korea.
Dae-Hyun YooDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea.
Bo Young YoonInje University Ilsan Paik Hospital, Goyang, Republic of Korea.
Sang-Cheol BaeDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, 133-792, Republic of Korea. scbae@hanyang.ac.kr.
Eui-Kyung LeeSchool of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-Gu, Suwon, Gyeonggi-do, 440-746, Republic of Korea. ekyung@skku.edu.ORCID http://orcid.org/0000-0003-0601-7754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to estimate the mapping model for EuroQol-5D (EQ-5D) utility values using the health assessment questionnaire disability index (HAQ-DI), pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) in a large, nationwide cohort of rheumatoid arthritis (RA) patients in Korea. The KORean Observational study Network for Arthritis (KORONA) registry data on 3557 patients with RA were used. Data were randomly divided into a modeling set (80 % of the data) and a validation set (20 % of the data). The ordinary least squares (OLS), Tobit, and two-part model methods were employed to construct a model to map to the EQ-5D index. Using a combination of HAQ-DI, pain VAS, and DAS28, four model versions were examined. To evaluate the predictive accuracy of the models, the root-mean-square error (RMSE) and mean absolute error (MAE) were calculated using the validation dataset. A model that included HAQ-DI, pain VAS, and DAS28 produced the highest adjusted R (2) as well as the lowest Akaike information criterion, RMSE, and MAE, regardless of the statistical methods used in modeling set. The mapping equation of the OLS method is given as EQ-5D = 0.95-0.21 × HAQ-DI-0.24 × pain VAS/100-0.01 × DAS28 (adjusted R (2) = 57.6 %, RMSE = 0.1654 and MAE = 0.1222). Also in the validation set, the RMSE and MAE were shown to be the smallest. The model with HAQ-DI, pain VAS, and DAS28 showed the best performance, and this mapping model enabled the estimation of an EQ-5D value for RA patients in whom utility values have not been measured.

Indexed as

Disability EvaluationPain MeasurementSurveys and QuestionnairesAdolescentAdultAgedAged, 80 and overArthritis, RheumatoidCost-Benefit AnalysisFemaleHealth Care CostsHealth ResourcesHumansLeast-Squares AnalysisLinear ModelsMaleDAS28EQ-5DHAQ-DIMappingUtility

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.