SynthesisBMC neurology2016
Neurological presentations of intravascular lymphoma (IVL): meta-analysis of 654 patients.
Synthesis in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- [Intravascular large B-cell lymphoma of the nasal turbinate presenting with hemophagocytic lymphohistiocytosis: a case report and literature review].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025Review
- Intravascular large B-cell lymphoma presenting as encephalomyelitis diagnosed by renal biopsy: a case report.BMC neurology · 2025Article
- Case Report: Neuropsychological Profile of a Patient With Intravascular Large B-Cell Lymphoma Following Infection and Vaccination.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- MR findings of intravascular large B-cell lymphoma of the central nervous system: report of three cases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- A Rare Case of Adrenal Intravascular Large B-Cell Lymphoma Diagnosed via Percutaneous Needle Biopsy.World journal of surgical oncology · 2025Article
- Article
- Intravascular Large B-Cell Lymphoma Diagnosed After Recurrent Stroke: Case Report and Literature Review.Neurology international · 2025Article
- Cognitive Dysfunction as an Initial Manifestation of Rheumatoid Arthritis-associated Intravascular Large B-cell Lymphoma.Internal medicine (Tokyo, Japan) · 2025Review
- Unveiling the Clinical and Imaging Signatures of Intravascular Lymphoma of the Central Nervous System: A Multicentric Cohort Study.Annals of neurology · 2025Article
- Clinical manifestations and outcomes of patients with intravascular large B-cell lymphoma with neurological involvement: highlighting longitudinally extensive myelopathy as a distinct feature.BMJ neurology open · 2025Article
- Rare intravascular large B-cell lymphoma (IVLBCL) can cause atypical intracerebral haemorrhage and mislead diagnostics.BMJ case reports · 2024Article
- Case report: Intravascular large B cell lymphoma mimicking acute demyelinating encephalomyelitis after SARS-CoV-2 reinfection: diagnostic value of advanced MRI techniques and the literature review with the assistance of ChatGPT.Frontiers in immunology · 2024Review
- Rare Case of Refractory Shock Secondary to Large B Cell Lymphoma.Journal of Brown hospital medicine · 2024Article
- Rapidly progressive dementia due to intravascular lymphoma: A prion disease reference center experience.European journal of neurology · 2024Article
- Review
- Article
- Asian variant intravascular large B-cell lymphoma with highly suspected central nervous system involvement: A case report.World journal of clinical cases · 2023Article
- Intravascular Lymphoma as a Cause of Recurrent Strokes - Case Report and Review of the Literature.The Neurohospitalist · 2023Article
- Intravascular lymphoma presenting as longitudinally extensive myelitis: a remarkable diagnostic challenge.Acta neurologica Belgica · 2023Article
- Mononeuropathy multiplex as an uncommon presentation of intravascular lymphoma: A case report.Clinical case reports · 2023Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with intravascular lymphoma (IVL) frequently have neurological signs and symptoms. Prompt diagnosis and treatment is therefore crucial for their survival. However, the spectrum of neurological presentations and their respective frequencies have not been adequately characterized. Our aim is to document the spectrum of clinical symptoms and their respective frequencies and to create a clinical framework for the prompt diagnosis of IVL.
methodsA comprehensive meta-analysis of 654 cases of IVL published between 1957 and 2012 was performed to provide better insight into the neurological presentations of this disease. Neurologic complications were mainly divided into central nervous system (CNS) and peripheral nervous system (PNS) presentations.
resultsThere were no differences in occurrences of CNS IVL based on gender or geographic locations (Asian Vs non-Asian). However, most patients with CNS IVL were younger than 70 years of age (p < 0.05). Our limited data do not support the treatment efficacy of methotrexate. CNS symptoms were seen in 42% of all cases. The most common CNS complications identified were cognitive impairment/dementia (60.9%), paralysis (22.2%), and seizures (13.4%). PNS complications were seen in 9.5% of cases. Out of these, muscle weakness (59.7%), neurogenic bladder (37.1%), and paresthesia (16.1%) were the most common presentations.
conclusionsCNS complications are more common among IVL patients. Out of these, dementia and seizures outnumber stroke-like presentations.
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