Evidence map›Paper›PMID 26849801›Full record

ArticlePloS one2016

The Increasing Trend in Caesarean Section Rates: Global, Regional and National Estimates: 1990-2014.

Ana Pilar Betrán, Jianfeng Ye, Anne-Beth Moller, Jun Zhang, A Metin Gülmezoglu, Maria Regina Torloni

14 registry-linked trialsAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 14 registered trials, which are not on this map. Cited by 844 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
844citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02785094 completednot on this map

Education and Social Media Versus Non-Indicated Caesarean Section Rate in Egypt

TypeobservationalSponsorTalkha Central HospitalRan2016 to 2016Enrolled1,400ConditionsComplications, Cesarean SectionArmsObservation
NCT03794063 unknown statusnot on this mapstarted 2019, after this paper: background citation

Analysis of Caesarean Section Rate According to the 10 Group Robson Classification; A Multicenter Prospective Study in Egypt

Typeobservational_patient_registrySponsorEgyptian Society of Royal College of Obstetricians and GynaecologistsRan2019 to 2019Enrolled3,000ConditionsCaesarean Section RateArmsRobson 10 group classification system
NCT04211597 nacompletednot on this mapstarted 2017, after this paper: background citation

EGF-loaded Chitosan to Facilitate Epithelial Healing And Prevent Scar Formation of Cesarean Wound

TypeinterventionalSponsorChang Gung Memorial HospitalRan2017 to 2018Enrolled60ConditionsCesarean Wound, Scar, Previous Cesarean Section, Complicating Pregnancy or Childbirth, Affecting Fetus or NewbornArmsControl, Silicone gel, microencapsulated polysaccharide and oligopeptide-1(Me-EGF) 40 mcg & 5 mcg
NCT04385680 phase1 / phase2completednot on this mapstarted 2020, after this paper: background citation

The Impact of Chlorhexidine Preoperative Vaginal Preparation in Reducing the Post-cesarean Endometritis and Sepsis for Cases in Labor. A Randomized Controlled Trial

TypeinterventionalSponsorZagazig UniversityRan2020 to 2022Enrolled840ConditionsPostpartum Endometritis, Wound Infection, Chlorhexidine Adverse Reaction, Postoperative FeverArmsChlorhexidine Gluconate vaginal solution 0.05%
NCT04504500 nacompletednot on this mapstarted 2021, after this paper: background citation

Reducing the Cesarean Section Rates and Enhancing Vaginal Delivery in Greece Through Educational, Behavioral and Organizational Interventions in Labor Management: a Stepped-Wedge Randomized Controlled Trial (ENGAGE Trial)

TypeinterventionalSponsorHellenic Society of Obstetrics and GynecologyRan2021 to 2023Enrolled6,029ConditionsCesarean Section RatesArmsHSOG guidelines application, Interactive workshops and courses, Feedback through follow-up meetings, Robson criteria usage, Access to live real-time statistics
NCT04667000 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect Of Forced Air Warming Used For Different Body Parts During Caseraen Section On Maternal Hypothermia, Shivering, Thermal Comfort, Apgar Score And Breastfeeding: Randomized Controlled Trial

TypeinterventionalSponsorHacettepe UniversityRan2021 to 2022Enrolled35ConditionsCesarean Section Complications, HypothermiaArmsForced Air Warming
NCT04911322 completednot on this mapstarted 2021, after this paper: background citation

Correlation Between Pulmonary Artery Doppler And Other Ultrasonographic Markers With Neonatal Outcome In Placenta Accreta Spectrum Patients

TypeobservationalSponsorCairo UniversityRan2021 to 2022Enrolled71ConditionsPlacenta AccretaArmsultrasonography
NCT05672563 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Cesarean Scar Evaluation Using Saline Infusion Sonography in Women With Previous Pregnancy in Scar

TypeinterventionalSponsorAssaf-Harofeh Medical CenterRan2023 to 2023Enrolled40ConditionsUterus, ScarArmsSaline infusion sonography for evaluation of cesarean scar
NCT05777837 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Laparoscopic Excision Versus Combined Hysteroscopic and Laparoscopic Repair Without Excision of Large Cesarean Scar Niche: A Randomized Controlled Trial

TypeinterventionalSponsorZagazig UniversityRan2023 to 2024Enrolled30ConditionsCesarean Scar NicheArmslaparoscopic repair of cesarean scar niche, Combined hysteroscopic and laparoscopic repair of cesarean scar niche
NCT06160583 completednot on this mapstarted 2023, after this paper: background citation

General Anesthesia in Obstetric Patients for Cesarean Section, Maternal and Perinatal Outcomes

Typeobservational_patient_registrySponsorHospital Civil de GuadalajaraRan2023 to 2024Enrolled5,000ConditionsAnesthesia, Perinatal Morbidity, Maternal-Fetal Relations
NCT06257940 unknown statusnot on this mapstarted 2023, after this paper: background citation

Impact of Changing Sterile Glove at the Time of Wound Closure to Reduce Surgical Site Infection in Women Undergoing Elective Cesarean Section; a Prospective Randomized Controlled Clinical Trial

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled220ConditionsCesarean Section Complications
NCT06620432 narecruitingnot on this mapstarted 2025, after this paper: background citation

High Segmental Hysterotomy vs. Low Segmental Hysterotomy: Association With the Incidence of Uterine Wall Defects After Cesarean Section

TypeinterventionalSponsorFundacion Clinica Valle del LiliRan2025 to 2027Enrolled168ConditionsPlacenta Accreta SpectrumArmsLow segment hysterotomy, High segment hysterotomy, Crossed hysterorrhaphy, Non-Crossed hysterorrhaphy
NCT07601542 nacompletednot on this mapstarted 2025, after this paper: background citation

Evaluation of Ultrasound Assisted Localisation of the Intervertebral Space Versus the Traditional Landmark Technique During Subarachnoid Block for Caesarean Section in Obese Parturient

TypeinterventionalSponsorBangladesh Medical UniversityRan2025 to 2025Enrolled60ConditionsCesarean Section, Obese Parturient, Ultrasound Guided Subarachnoid BlockArmsLandmark-Guided Spinal Anesthesia, Ultrasound-Assisted Spinal Anesthesia
NCT07730060 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Intraperitoneal Saline Irrigation in Cesarean Section: Effect on Postoperative Infectious Morbidity and Paralytic Ileus ,Randomized Controlled Study.

TypeinterventionalSponsorAssiut UniversityRan2026 to 2027Enrolled150ConditionsCesarean SectionArmsIntraperitoneal Saline Irrigation
3 · Its place in the literature

Who cites it

844 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  5. Obesity and asthma during pregnancy: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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784 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Pilar BetránUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Jianfeng YeDepartment of Clinical Epidemiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Anne-Beth MollerUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Jun ZhangMinistry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
A Metin GülmezogluUNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
Maria Regina TorloniEvidence Based Healthcare Post-Graduate Program, Department of Medicine, São Paulo Federal University, São Paulo, Brazil.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundCaesarean section (CS) rates continue to evoke worldwide concern because of their steady increase, lack of consensus on the appropriate CS rate and the associated additional short- and long-term risks and costs. We present the latest CS rates and trends over the last 24 years.

methodsWe collected nationally-representative data on CS rates between 1990 to 2014 and calculated regional and subregional weighted averages. We conducted a longitudinal analysis calculating differences in CS rates as absolute change and as the average annual rate of increase (AARI).

resultsAccording to the latest data from 150 countries, currently 18.6% of all births occur by CS, ranging from 6% to 27.2% in the least and most developed regions, respectively. Latin America and the Caribbean region has the highest CS rates (40.5%), followed by Northern America (32.3%), Oceania (31.1%), Europe (25%), Asia (19.2%) and Africa (7.3%). Based on the data from 121 countries, the trend analysis showed that between 1990 and 2014, the global average CS rate increased 12.4% (from 6.7% to 19.1%) with an average annual rate of increase of 4.4%. The largest absolute increases occurred in Latin America and the Caribbean (19.4%, from 22.8% to 42.2%), followed by Asia (15.1%, from 4.4% to 19.5%), Oceania (14.1%, from 18.5% to 32.6%), Europe (13.8%, from 11.2% to 25%), Northern America (10%, from 22.3% to 32.3%) and Africa (4.5%, from 2.9% to 7.4%). Asia and Northern America were the regions with the highest and lowest average annual rate of increase (6.4% and 1.6%, respectively).

conclusionThe use of CS worldwide has increased to unprecedented levels although the gap between higher- and lower-resource settings remains. The information presented is essential to inform policy and global and regional strategies aimed at optimizing the use of CS.

Indexed as

AfricaAsiaCaribbean RegionCesarean SectionDeveloped CountriesDeveloping CountriesEuropeFemaleHumansLatin AmericaNorth AmericaOceaniaPregnancy

Identifiers

PMID26849801
PMCPMC4743929

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.