Evidence map›Paper›PMID 26849401›Full record

ArticlePediatric transplantation2016

Same sibling marrow following cord allogeneic transplantation as therapy for second relapse acute promyelocytic leukemia in a pediatric patient.

Satiro N De Oliveira, Roy L Kao, Andrew Pham, LaMarr Taylor Smith, Pamela Kempert, Theodore B Moore

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PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Satiro N De OliveiraDepartment of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Roy L KaoDivision of Hematology/Oncology, Mattel Children's Hospital-UCLA Medical Center, Los Angeles, CA, USA.
Andrew PhamDepartment of Internal Medicine, Scripps Mercy Hospital, San Diego, CA, USA.
LaMarr Taylor SmithDivision of Hematology/Oncology, Mattel Children's Hospital-UCLA Medical Center, Los Angeles, CA, USA.
Pamela KempertDepartment of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Theodore B MooreDepartment of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ronald Reagan UCLA Medical Center · USMattel Children's Hospital · USScripps Mercy Hospital · USUCLA Medical Center · USUniversity of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA Child Health Research Career Development AwardK12HD034610 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEVASKAR, SHERIN U · 2002 to 2017
$6.6M
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NICHD NIH HHS K12 HD034610
6 · The paper itself

Abstract

Optimal therapy for relapsed APL in pediatric patients is controversial. Allogeneic HSCT is an alternative, with event-free survival of 70-75%. We report a pediatric patient with APL who relapsed 28 months after CBT from her sibling and then was treated with BMT from the same donor. Bone marrow was selected for higher cell dose, donor availability, and partial donor chimerism. Persistent molecular remission was achieved, currently at 65 months after BMT. This case suggests the potential role of GVL activity in APL and illustrates the use of different cell sources from the same donor in allogeneic transplantation for pediatric patients.

Indexed as

Bone Marrow CellsBone Marrow TransplantationChildChild, PreschoolCord Blood Stem Cell TransplantationFemaleGraft vs Host DiseaseHLA AntigensHumansLeukemia, Promyelocytic, AcuteMaleRecurrenceRemission InductionSiblingsTime FactorsTissue DonorsHLA Antigensacute promyelocytic leukemiabone marrow transplantgraft-versus-leukemiaumbilical cord blood

Identifiers

PMID26849401
PMCPMC4807975
OpenAlexW2253087403

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.