Evidence map›Paper›PMID 26848812›Full record

ArticleClinical cardiology2016

Comparison of Coronary Artery Disease Consortium 1 and 2 Scores and Duke Clinical Score to Predict Obstructive Coronary Disease by Invasive Coronary Angiography.

João Almeida, Paulo Fonseca, Tiago Dias, Ricardo Ladeiras-Lopes, Nuno Bettencourt, José Ribeiro, Vasco Gama

Abstract readComparative Study
In one paragraph

Article in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Pretest models for predicting abnormal stress single-photon emission computed tomography myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

João AlmeidaDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
Paulo FonsecaDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
Tiago DiasDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
Ricardo Ladeiras-LopesDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
Nuno BettencourtDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
José RibeiroDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.
Vasco GamaDepartment of Cardiology, Gaia/Espinho Hospital Center, Vila Nova de Gaia, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe first step in evaluating a patient with suspected stable coronary artery disease (CAD) is the determination of the pretest probability. The European Society of Cardiology guidelines recommend the use of the CAD Consortium 1 score (CAD1), which contrary to CAD Consortium 2 (CAD2) score and Duke Clinical Score (DCS), does not include modifiable cardiovascular risk factors. HYPOTHESIS: Using scores that include modifiable risk factors (DCS and CAD2) enhances prediction of CAD.

methodsWe retrospectively included all patients referred to invasive coronary angiography for suspected CAD from January/2008-December/2012 (N = 2234). Pretest probability was calculated using 3 models (CAD1, DCS, and CAD2), and they were compared using the net reclassification improvement.

resultsMean patient age was 63.7 years, 67.5% were male, and the majority (66.9%) had typical angina. Coronary artery disease was diagnosed in 58.5%, and the area under the curve was 0.685 for DCS, 0.664 for CAD1, and 0.683 for CAD2, with a statistically significant difference between CAD1 and the others (P < 0.001). The net reclassification improvement was 20% for DCS, related to adequate reclassification of 32% of patients with CAD to a higher risk category, and 5% for CAD2, at the cost of adequate reclassification of 34% of patients without CAD to a lower risk category.

conclusionsPrediction of CAD using scores that include modifiable cardiovascular risk factors seems to improve accuracy. Our results suggest that, in high-prevalence populations, DCS may better identify patients at higher risk and CAD2 those at lower risk for CAD.

Indexed as

Coronary AngiographyDecision Support TechniquesAgedArea Under CurveCoronary Artery DiseaseCoronary StenosisFemaleHumansMaleMiddle AgedModels, StatisticalPortugalPredictive Value of TestsPrognosisRadiographic Image Interpretation, Computer-AssistedReproducibility of Results

Identifiers

PMID26848812
PMCPMC6490804

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.