ReviewInternational journal of molecular sciences2016
Molecular Mechanisms of Nickel Allergy.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 166 citations in OpenAlex.
- Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver.Journal of applied toxicology : JAT · 2026Article
- Systemic Inflammatory Symptoms Following Mastectomy With Nickel-Containing Surgical Clips: A Case Report.Cureus · 2026Article
- Analysis of Ni, Cu, and Fe in Loose Cosmetic Products: A Preliminary Dermal Exposure and Health Risk Assessment.Toxics · 2026Article
- Ultra-High-Molecular-Weight Polyethylene Cables for Sternal Closure in a Metal-Allergic Patient With Stanford Type A Acute Aortic Dissection: A Case Report.Clinical case reports · 2026Article
- Concentrations and Probabilistic Health Risks of Seven Metals in Face and Eye Cosmetics Across Seven Asian Countries.Toxics · 2026Article
- Visualizing the distribution of various inorganic metals in brown rice by radiotracer experiments.Metallomics : integrated biometal science · 2026Article
- The Nallan-Nickel Effect: A Mechanistic Perspective on Burning Sensations and Lichenoid Reactions in Long-Serving Porcelain-Fused-to-Metal Restorations.Dentistry journal · 2025Article
- Management of Patients with Nickel Hypersensitivity Undergoing Patent Foramen Ovale Closure.Journal of clinical medicine · 2025Article
- Nickel-induced labial angioedema in a pediatric patient with orthodontic braces: a case report.Italian journal of pediatrics · 2025Article
- Adopting orphan receptors: zebrafish Tlr4 homologs mediate responses to group IX/X transition metals.Frontiers in immunology · 2025Article
- Associations among environmental exposure to trace elements and biomarkers of early kidney damage in the pediatric population.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- Exposure to Nickel-Cadmium Contamination of Drinking Water Culminates in Liver Cirrhosis, Renal Azotemia, and Metabolic Stress in Rats.Biological trace element research · 2024Article
- Metal mixtures associate with higher amyotrophic lateral sclerosis risk and mortality independent of genetic risk and correlate to self-reported exposures: a case-control study.medRxiv : the preprint server for health sciences · 2024Article
- Food Intolerances, Food Allergies and IBS: Lights and Shadows.Nutrients · 2024Review
- Countenance and implication of Β-sitosterol, Β-amyrin and epiafzelechin in nickel exposed Rat: in-silico and in-vivo approach.Scientific reports · 2023Article
- Application of amino-hypophosphite polyampholyte for purification of wastewater containing Ni(ii) ions.RSC advances · 2023Article
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- Nickel ions influence the transepithelial sodium transport in the trachea, intestine and skin.Scientific reports · 2023Article
- Identification of microRNA Signatures in Peripheral Blood of Young Women as Potential Biomarkers for Metal Allergy.Biomedicines · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic contact hypersensitivity to metals is a delayed-type allergy. Although various metals are known to produce an allergic reaction, nickel is the most frequent cause of metal allergy. Researchers have attempted to elucidate the mechanisms of metal allergy using animal models and human patients. Here, the immunological and molecular mechanisms of metal allergy are described based on the findings of previous studies, including those that were recently published. In addition, the adsorption and excretion of various metals, in particular nickel, is discussed to further understand the pathogenesis of metal allergy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.