Evidence map›Paper›PMID 26848649›Full record

ReviewMolecules (Basel, Switzerland)2016

Elicitation, an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories.

Karla Ramirez-Estrada, Heriberto Vidal-Limon, Diego Hidalgo, Elisabeth Moyano, Marta Golenioswki, Rosa M Cusidó, Javier Palazon

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed.

  1. Chitosan activates a sequential CaPlant signaling & behavior · 2026
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  4. Review
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  6. Article
  7. Article
  8. Synergistic effects of HBMC plant biology · 2026
    Article
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  10. Review
  11. Article
  12. Article
  13. Hybrid Poly(Lactic)-Chitosan Scaffold Intensifying In Situ Bioprocessing ofInternational journal of molecular sciences · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karla Ramirez-EstradaLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. kems3estrada@gmail.com.
Heriberto Vidal-LimonLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. bioraf@hotmail.com.
Diego HidalgoLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. diegoahmz@hotmail.com.
Elisabeth MoyanoLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. elisabeth.moyano@upf.edu.
Marta GolenioswkiArgentina National Rechearch Council (Conicet), Ministry of Science and Technology, Arenales 230. B. Junior, Córdoba X5000APP, Argentina. mgoleniowski@gmail.com.
Rosa M CusidóLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. rcusido@ub.edu.
Javier PalazonLaboratori de Fisiologia Vegetal, Facultat de Farmacia, Universitat de Barcelona, Av. Joan XXIII sn, Barcelona 08028, Spain. javierpalazon@ub.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant in vitro cultures represent an attractive and cost-effective alternative to classical approaches to plant secondary metabolite (PSM) production (the "Plant Cell Factory" concept). Among other advantages, they constitute the only sustainable and eco-friendly system to obtain complex chemical structures biosynthesized by rare or endangered plant species that resist domestication. For successful results, the biotechnological production of PSM requires an optimized system, for which elicitation has proved one of the most effective strategies. In plant cell cultures, an elicitor can be defined as a compound introduced in small concentrations to a living system to promote the biosynthesis of the target metabolite. Traditionally, elicitors have been classified in two types, abiotic or biotic, according to their chemical nature and exogenous or endogenous origin, and notably include yeast extract, methyl jasmonate, salicylic acid, vanadyl sulphate and chitosan. In this review, we summarize the enhancing effects of elicitors on the production of high-added value plant compounds such as taxanes, ginsenosides, aryltetralin lignans and other types of polyphenols, focusing particularly on the use of a new generation of elicitors such as coronatine and cyclodextrins.

Indexed as

BiotechnologyAcetatesCyclodextrinsCyclopentanesGinsenosidesIn Vitro TechniquesLignansOxylipinsPlant CellsTaxoidsAcetatesCyclodextrinsCyclopentanesGinsenosidesLignansmethyl jasmonateOxylipinsTaxoidselicitorsplant cell factoriesplant secondary metabolismsecondary compound production

Identifiers

PMID26848649
PMCPMC6273650

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.