Evidence map›Paper›PMID 26848560›Full record

Observational studyClinical cardiology2016

Predictors of Medical Management in Patients Undergoing Elective Cardiac Catheterization for Chronic Ischemic Heart Disease.

Auras R Atreya, Senthil K Sivalingam, Sonali Arora, Mohammad Amin Kashef, Janice Fitzgerald, Paul Visintainer, Amir Lotfi, Michael B Rothberg

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Clinical cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Auras R AtreyaDivision of Cardiovascular Medicine, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Senthil K SivalingamDivision of Cardiovascular Medicine, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Sonali AroraDivision of Cardiovascular Medicine, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Mohammad Amin KashefDivision of Cardiovascular Medicine, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Janice FitzgeraldFaculty and Resident Development, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Paul VisintainerDivision of Epidemiology and Biostatistics, Baystate Medical Center, Springfield, Massachusetts.
Amir LotfiDivision of Cardiovascular Medicine, Department of Internal Medicine, Baystate Medical Center, Springfield, Massachusetts.
Michael B RothbergCenter for Value-Based Care Research, Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
Baystate Medical Center · USCleveland Clinic · USTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCompared with medical therapy, percutaneous coronary intervention (PCI) does not reduce mortality or myocardial infarction in patients with stable angina. Therefore, PCI should be guided by refractory anginal symptoms and not just lesion characteristics. HYPOTHESIS: We hypothesized that angiographic lesion characteristics and stress test results would have a greater role in the decision to proceed with PCI than would symptom severity.

methodsWe performed a retrospective cohort study of patients undergoing elective cardiac catheterization and possible PCI at an academic medical center. Anginal symptoms, optimal medical therapy, antianginal therapy, stress test results, and angiographic lesions (including American College of Cardiology/American Heart Association [ACC/AHA] lesion type) were analyzed. Logistic regression was used to determine predictors of medical management among patients not referred for coronary artery bypass surgery.

resultsOf the 207 patients with obstructive lesions amenable to PCI, 163 underwent PCI and 44 were referred to medical therapy. In the multivariable logistic model, the following variables were associated with medical management: advancing age (odds ratio [OR] per 1 year: 0.94, 95% confidence interval [CI]: 0.91-0.98), chronic kidney disease (OR: 0.23, 95% CI: 0.06-0.95), distal location (OR: 0.21, 95% CI: 0.09-0.48), and ACC/AHA type C lesion (OR: 0.08, 95% CI: 0.03-0.22). There was no association with sex, race, symptoms, optimal medical therapy, maximal antianginal therapy, referral status, or type of interventional cardiologist (academic vs private practice).

conclusionsFor patients undergoing cardiac catheterization for stable angina, the decision to proceed to PCI vs medical management appears to depend largely on patient and angiographic characteristics, but not on symptoms or ischemia. Distal and high-risk lesions (ACC/AHA type C) are more often referred for medical therapy.

Indexed as

Cardiac CatheterizationCoronary AngiographyPercutaneous Coronary InterventionAcademic Medical CentersAgedAged, 80 and overAge FactorsAngina, StableCardiovascular AgentsExercise TestFemaleHumansKidney DiseasesLogistic ModelsMaleMassachusettsCardiovascular Agents

Identifiers

PMID26848560
PMCPMC6490706
OpenAlexW2288306521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.