ArticleIranian journal of pediatrics2016
Evaluation oF Epicardial Fat and Carotid Intima-Media Thickness in Obese Children.
Article in Iranian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Myocardial Performance Index and Carotid Intima-Media Thickness in Children with Metabolically Healthy and Metabolically Unhealthy ObesityJournal of clinical research in pediatric endocrinology · 2026Article
- Carotid intima medial thickness and its association with cardiometabolic risk factors in children with overweight and obesity: a hospital-based cross-sectional study.The British journal of nutrition · 2025Article
- Assessment of Epicardial Fat in Children: Its Role as a Cardiovascular Risk Factor and How It Is Influenced by Lifestyle Habits.Nutrients · 2024Review
- C-Reactive Protein as a Marker of Inflammation in Children and Adolescents with Metabolic Syndrome: A Systematic Review and Meta-Analysis.Biomedicines · 2023Review
- Epicardial Adipose Tissue: A Piece of The Puzzle in Pediatric Hypertension.Journal of clinical medicine · 2023Article
- Article
- Perirenal and epicardial fat and their association with carotid intima-media thickness in children.Annals of pediatric endocrinology & metabolism · 2019Article
- Insulin metabolism markers are predictors of subclinical atherosclerosis among overweight and obese children and adolescents.BMC pediatrics · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpicardial fat has a role in cardiovascular diseases.
objectivesTo assess epicardial fat and its relation with carotid intima-media thickness (IMT) in obese adolescents with metabolic syndrome (MetS). PATIENTS AND
methodsThe study included 60 obese adolescents and 25 control subjects. According to the presence or absence of MetS, obese subjects were divided into two subgroups. We measured weight, height, calculated Body Mass Index, waist circumference, hip circumference, systolic blood pressure, diastolic blood pressure and biochemical parameters (fasting glucose, total cholesterol, triglycerides, high density lipoprotein cholesterol, and low density lipoprotein cholesterol, High sensitivity C-reactive protein, fasting insulin, a homeostasis model assessment index of insulin resistance. plus an echocardiographic examination with measurement of epicardial adipose tissue thickness (EATT).
resultsLeft ventricular mass index measurements were significantly higher in MetS group than both non-MS and control groups. The MetS and non-MetS obese patients had significantly higher carotid IMT in comparison to the control group. Carotid IMT measurements were significantly higher in MetS group had than both non-MetS and control groups. Also, EATT was significantly increased in patients with MetS compared to control group. Among MetS obese group, EATT was positively correlated with body mass index-standard deviation score, waist circumference, fasting glucose, fasting insulin, insulin resistance, triglyceride levels, left ventricular thickness, left ventricular mass index and myocardial performance index. EATT was found to be the only predictor of carotid IMT.
conclusionsEATT is closely related to carotid IMT and early cardiac dysfunction in obese adolescents with MetS.
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