Evidence map›Paper›PMID 26848308›Full record

ArticleChemistry Central journal2016

Compositional difference in antioxidant and antibacterial activity of all parts of the Carica papaya using different solvents.

Nazia Asghar, Syed Ali Raza Naqvi, Zaib Hussain, Nasir Rasool, Zulfiqar Ali Khan, Sohail Anjum Shahzad, Tauqir A Sherazi, Muhammad Ramzan Saeed Ashraf Janjua, Saeed Ahmad Nagra, Muhammad Zia-Ul-Haq and 1 more

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Article in Chemistry Central journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Journal of experimental pharmacology · 2026
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  3. Various parts ofFrontiers in molecular biosciences · 2026
    Review
  4. Review
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  7. Chilean papaya (Heliyon · 2024
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  8. Article
  9. Article
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  11. Article
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  13. Effects of the Seed Oil ofMolecules (Basel, Switzerland) · 2022
    Article
  14. Antiviral & platelet-protective properties ofThe Indian journal of medical research · 2022
    Article
  15. Oxidative medicine and cellular longevity · 2022
    Review
  16. Article
  17. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  18. Bioassay studies on the reaction ofSaudi journal of biological sciences · 2020
    Article
  19. Anti-obesity effect ofBiomedical reports · 2020
    Article
  20. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Nazia AsgharDepartment of Chemistry, Government College University, Faisalabad, 38000 Pakistan.
Syed Ali Raza NaqviDepartment of Chemistry, Government College University, Faisalabad, 38000 Pakistan.
Zaib HussainInstitute of Chemistry, University of the Punjab, Lahore, 54000 Pakistan.
Nasir RasoolDepartment of Chemistry, Government College University, Faisalabad, 38000 Pakistan.
Zulfiqar Ali KhanDepartment of Chemistry, Government College University, Faisalabad, 38000 Pakistan.
Sohail Anjum ShahzadDepartment of Chemistry, COMSATS Institute of Information Technology, Abbottabad, 22060 Pakistan.
Tauqir A SheraziDepartment of Chemistry, COMSATS Institute of Information Technology, Abbottabad, 22060 Pakistan.
Muhammad Ramzan Saeed Ashraf JanjuaDepartment of Chemistry, University of Sargodha, Sargodha, 40100 Pakistan.
Saeed Ahmad NagraInstitute of Chemistry, University of the Punjab, Lahore, 54000 Pakistan.
Muhammad Zia-Ul-HaqThe Patent Office, Karachi, Pakistan.
Hawa Ze JaafarDepartment of Crop Science, Faculty of Agriculture, UPM, 43400 Serdang, Selangor Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarica papaya is a well known medicinal plant used in the West and Asian countries to cope several diseases. Patients were advised to eat papaya fruit frequently during dengue fever epidemic in Pakistan by physicians. This study was conducted to establish Polyphenols, flavonoids and antioxidant potential profile of extracts of all major parts of the C. papaya with seven major solvents i.e. water, ethanol, methanol, n-butanol, dichloromethane, ethyl acetate, and n-hexane.

resultsTPC, TFC, antioxidant and antibacterial potential were determined using different aqueous and organic solvents in addition to the determination of trace element in leaves, pulp and peel of C. papaya. Total soluble phenolics and flavonoids were found in promising quantity (≈66 mg GAE/g) especially in case of methanol and ethanol extracts. Antioxidant activity using DPPH free radical scavenging assay indicated leaves, bark, roots and pulp extracts showed >75.0 % scavenging potential while leaves and pulp showed 84.9 and 80.9 % inhibition of peroxidation, respectively. Reducing power assay showed leaves, pulp and roots extracts active to reduce Fe(3+) to Fe(2+) ions. The antibacterial study showed pulp extract is the best to cope infectious action of bacteria.

conclusionThis study was conducted to test the medicinal profile of all parts of C. papaya by extracting secondary metabolites with organic and aqueous solvents. Ethanol and methanol both were found to be the best solvents of choice to extract natural products to get maximum medicinal benefits and could be used to medicinal formulation against different infectious diseases.Graphical abstractMedicinal evaluation of different parts of C. papaya.

Identifiers

PMID26848308
PMCPMC4741006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.