Trial reportClinical interventions in aging2016
Association between frailty and delirium in older adult patients discharged from hospital.
Trial report in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04056871 (Comparing the Association of Different Frailty Scores to the Incidence of Post-operative Delirium and Cognitive Dysfunction), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing the Association of Different Frailty Scores to the Incidence of Post-operative Delirium and Cognitive Dysfunction
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Delirium among older adults living at home: a systematic review of prevalence, incidence, and risk factors.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Pooled it
- Predisposing and Precipitating Factors Associated With Delirium: A Systematic Review.JAMA network open · 2023Pooled it
- The impact of interventions on management of frailty in hospitalized frail older adults: a systematic review and meta-analysis.BMC geriatrics · 2020Pooled it
- Companionship at hospital discharge and its association with subsequent delirium onset in older adults - the TRADE observational study.BMC geriatrics · 2026Observational
- Medication Use by Older Adults with Frailty: A Scoping Review.Pharmacy (Basel, Switzerland) · 2025Review
- The perceptions of European geriatricians on the co-occurrence and links between dementia, delirium and frailty.European geriatric medicine · 2025Article
- Associations of Frailty Status and Sleep Quality With Incident Delirium: A Prospective Study in the UK Biobank.CNS neuroscience & therapeutics · 2025Article
- Glaucoma Ex-PRESS Implantation Surgery: Is There a Difference in Efficacy and Safety between Inpatient and Outpatient Management?JMA journal · 2024Article
- To Be Frail or Not to Be Frail: This Is the Question-A Critical Narrative Review of Frailty.Journal of clinical medicine · 2024Review
- Article
- Association of frailty with health service use among older Chinese adults: analysis of population-based panel data.Frontiers in public health · 2023Article
- Survival of Frail Elderly with Delirium.International journal of environmental research and public health · 2022Article
- Use of the Patient-Generated Subjective Global Assessment to Identify Pre-Frailty and Frailty in Hospitalized Older Adults.The journal of nutrition, health & aging · 2021Article
- Prevalence and Risk Factors for Delirium in Elderly Patients With Severe Burns: A Retrospective Cohort Study.Journal of burn care & research : official publication of the American Burn Association · 2020Article
- The Association of a Frailty Index and Incident Delirium in Older Hospitalized Patients: An Observational Cohort Study.Clinical interventions in aging · 2020Observational
- Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day.BMC medicine · 2019Article
- Translating Frailty Research Into Clinical Practice: Insights From the Successful Aging and Frailty Evaluation Clinic.Journal of the American Medical Directors Association · 2019Article
- Operationalizing a frailty index using routine blood and urine tests.Clinical interventions in aging · 2017Article
- Comparing the predictive accuracy of frailty, comorbidity, and disability for mortality: a 1-year follow-up in patients hospitalized in geriatric wards.Clinical interventions in aging · 2017Article
- [A series of cases--too old for a pacemaker?].Wiener medizinische Wochenschrift (1946) · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDelirium and frailty - both potentially reversible geriatric syndromes - are seldom studied together, although they often occur jointly in older patients discharged from hospitals. This study aimed to explore the relationship between delirium and frailty in older adults discharged from hospitals.
methodsOf the 221 patients aged >65 years, who were invited to participate, only 114 gave their consent to participate in this study. Delirium was assessed using the confusion assessment method, in which patients were classified dichotomously as delirious or nondelirious according to its algorithm. Frailty was assessed using the Edmonton Frailty Scale, which classifies patients dichotomously as frail or nonfrail. In addition to the sociodemographic characteristics, covariates such as scores from the Mini-Mental State Examination, Instrumental Activities of Daily Living scale, and Cumulative Illness Rating Scale for Geriatrics and details regarding polymedication were collected. A multidimensional linear regression model was used for analysis.
resultsAlmost 20% of participants had delirium (n=22), and 76.3% were classified as frail (n=87); 31.5% of the variance in the delirium score was explained by frailty (R (2)=0.315). Age; polymedication; scores of the Confusion Assessment Method (CAM), instrumental activities of daily living, and Cumulative Illness Rating Scale for Geriatrics; and frailty increased the predictability of the variance of delirium by 32% to 64% (R (2)=0.64).
conclusionFrailty is strongly related to delirium in older patients after discharge from the hospital.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.