ArticleJournal of the American Society of Nephrology : JASN2016
Reduced Racial Disparity in Kidney Transplant Outcomes in the United States from 1990 to 2012.
Article in Journal of the American Society of Nephrology : JASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Risk Factors for 1-Year Graft Loss After Kidney Transplantation: Systematic Review and Meta-Analysis.Clinical journal of the American Society of Nephrology : CJASN · 2019Pooled it
- Effect of Race on Transplantation in Autosomal Dominant Polycystic Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Hybrid Telemedicine and In-Person Care for Kidney Transplant Follow-Up: A Qualitative Study.Clinical transplantation · 2025Article
- Multifaceted Intervention to Improve Graft Outcome Disparities in African American Kidney Transplants (MITIGAAT Study): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2024Article
- Identifying when racial and ethnic disparities arise along the continuum of transplant care: a national registry study.Lancet regional health. Americas · 2024Article
- Long-term outcomes in rapamycin on renal allograft function: a 30-year follow-up from a single-center experience.BMC nephrology · 2024Article
- Factors Influencing Kidney Transplantation Experiences for Patients From Culturally and Linguistically Diverse Backgrounds: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Trends in the survival benefit of repeat kidney transplantation over the past 3 decades.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023Article
- MyKidneyCoach, Patient Activation, and Clinical Outcomes in Diverse Kidney Transplant Recipients: A Randomized Control Pilot Trial.Transplantation direct · 2023Article
- Addressing kidney health disparities with new national policy: the time is now.Cardiovascular diagnosis and therapy · 2023Review
- Health inequities and the inappropriate use of race in nephrology.Nature reviews. Nephrology · 2022Review
- Long-term mortality among kidney transplant recipients with and without diabetes: a nationwide cohort study in the USA.BMJ open diabetes research & care · 2021Article
- Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Scalable Algorithms for Large Competing Risks Data.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2021Article
- The impact of time-varying clinical surrogates on disparities in African-American kidney transplant recipients - a retrospective longitudinal cohort study.Transplant international : official journal of the European Society for Organ Transplantation · 2019Article
- Better graft outcomes from offspring donor kidneys among living donor kidney transplant recipients in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- Pharmacist-Led, Technology-Assisted Study to Improve Medication Safety, Cardiovascular Risk Factor Control, and Racial Disparities in Kidney Transplant Recipients.Journal of the American College of Clinical Pharmacy : JACCP · 2018Article
- Transplant Center Variability in Disparities for African-American Kidney Transplant Recipients.Annals of transplantation · 2018Article
- Association of Citizenship Status With Kidney Transplantation in Medicaid Patients.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018Observational
- Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation.Transplantation · 2017Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Earlier studies reported inferior outcomes among black compared with white kidney transplant (KT) recipients. We examined whether this disparity improved in recent decades. Using the Scientific Registry of Transplant Recipients and Cox regression models, we compared all-cause graft loss among 63,910 black and 145,482 white adults who received a first-time live donor KT (LDKT) or deceased donor KT (DDKT) in 1990-2012. Over this period, 5-year graft loss after DDKT improved from 51.4% to 30.6% for blacks and from 37.3% to 25.0% for whites; 5-year graft loss after LDKT improved from 37.4% to 22.2% for blacks and from 20.8% to 13.9% for whites. Among DDKT recipients in the earliest cohort, blacks were 39% more likely than whites to experience 5-year graft loss (adjusted hazard ratio [aHR], 1.39; 95% confidence interval [95% CI], 1.32 to 1.47; P<0.001), but this disparity narrowed in the most recent cohort (aHR, 1.10; 95% CI, 1.03 to 1.18; P=0.01). Among LDKT recipients in the earliest cohort, blacks were 53% more likely than whites to experience 5-year graft loss (aHR, 1.53; 95% CI, 1.27 to 1.83; P<0.001), but this disparity also narrowed in the most recent cohort (aHR, 1.37; 95% CI, 1.17 to 1.61; P<0.001). Analyses revealed no statistically significant differences in 1-year or 3-year graft loss after LDKT or DDKT in the most recent cohorts. Our findings of reduced disparities over the last 22 years driven by more markedly improved outcomes for blacks may encourage nephrologists and patients to aggressively promote access to transplantation in the black community.
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Registered trials
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