Observational studyArchives of osteoporosis2016
Differences in the trajectory of bone mineral density change measured at the total hip and femoral neck between men and women following hip fracture.
Observational study in Archives of osteoporosis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The observation that older men suffer from hip fracture at DXA T-scores higher than older women and a proposal of a new low BMD category, osteofrailia, for predicting fracture risk in older men.Skeletal radiology · 2025Pooled it
- Effects of Multicomponent Home-Based Intervention on Muscle Composition, Fitness, and Bone Density After Hip Fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Physical function and lean body mass as predictors of bone loss after hip fracture: a prospective follow-up study.BMC musculoskeletal disorders · 2020Trial
- Observational
- Sex-specific associations of vitamin D and bone biomarkers with bone density and physical function during recovery from hip fracture: the Baltimore Hip Studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Sex differences and predictors of anti-osteoporosis medication use in the 12 months after hip fracture surgery in adults 65 or older.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- Article
- East Asians' T-scores for the diagnosis of osteoporosis should be calculated using ethnicity- and gender-specific BMD reference ranges: justifications.Skeletal radiology · 2024Review
- Site-Specific Differences in Bone Mineral Density of Proximal Femur Correlate with the Type of Hip Fracture.Diagnostics (Basel, Switzerland) · 2023Article
- Sex Differences in Recovery Across Multiple Domains Among Older Adults With Hip Fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Change in vertebral strength and bone mineral density in men and women over the year post-hip fracture: a subgroup analysis.Archives of osteoporosis · 2021Observational
- Comparing Longitudinal Sarcopenia Trends by Definitions Across Men and Women After Hip Fracture.Journal of the American Geriatrics Society · 2020Observational
- Article
- Article
- Incident fracture is associated with a period of accelerated loss of hip BMD: the Study of Osteoporotic Fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Soluble Tumor Necrosis Factor Alpha Receptor 1, Bone Resorption, and Bone Mineral Density in the Year Following Hip Fractures: The Baltimore Hip Studies.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018Article
- Human osteoblasts exhibit sexual dimorphism in their response to estrogen on microstructured titanium surfaces.Biology of sex differences · 2018Article
- Persistence of depressive symptoms and gait speed recovery in older adults after hip fracture.International journal of geriatric psychiatry · 2018Article
- Older men who sustain a hip fracture experience greater declines in bone mineral density at the contralateral hip than non-fractured comparators.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
unlabelledResearch has not examined changes in bone mineral density (BMD) between men and women following hip fracture. The aim was to evaluate sex differences in BMD following hip fracture. Men experienced significant declines in BMD, while not statistically greater than women, underscoring the necessity for better osteoporosis care in men.
introductionEach year in the USA, approximately 260,000 older adults experience a hip fracture. Women experiencing hip fracture have excess decline in BMD in the year following fracture compared to expected decrements due to aging, but few studies have assessed sex differences in the sequelae of hip fracture. Thus, our objective was to examine sex differences in BMD change in the year after hip fracture.
methodsThe sample (n = 286) included persons enrolled in the Baltimore Hip Studies 7th cohort, a study that matched (1:1) men and women experiencing hip fracture. Weighted estimating equations that accounted for missing data and selective survival were used to estimate sex differences in 12-month total hip (TH) and femoral neck (FN) BMD changes.
resultsMen had larger average adjusted percent decline in TH and FN BMD. Adjusted 12-month decreases at the FN showed a statistically significant decline of -4.60% (95% confidence interval [CI] -7.76%, -0.20%) in men and an insignificant change of -1.62% (95% CI -4.57%, 1.32%) in women. Yet, the difference in change between men and women was not statistically significant (P = 0.17). The estimated sex differences for TH BMD loss were smaller in magnitude.
conclusionsThere is evidence of significant BMD loss among men at the FN in the year after hip fracture. Although not statistically greater than women, these clinically significant findings highlight the need for improved osteoporosis care among men prior to and after hip fracture.
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