ArticleInternational journal of colorectal disease2016
Impact of reassessment of colonic hyperplastic polyps by expert GI pathologists.
Article in International journal of colorectal disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Randomized Comparison of the Adenoma Detection Rate in Screening Colonoscopy With and Without a Disposable Cap (ENDOCUFF VISION®)
Prospective Randomized Study on the Use of Artificial Intelligence (Fujifilm) for Polyp Detection in Colonoscopy
Who cites it
13 citing papers in PubMed.
- Serrated Polyps in Inflammatory Bowel Disease Indicate a Similar Risk of Metachronous Colorectal Neoplasia as in the General Population.Digestive diseases and sciences · 2024Article
- Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp.Human pathology · 2023Article
- Sporadic hyperplastic polyp associated with above-average risk of developing metachronous colorectal cancer.American journal of cancer research · 2023Article
- Endoscopists performance in optical diagnosis of colorectal polyps in artificial intelligence studies.United European gastroenterology journal · 2022Review
- Accuracy in optical diagnosis for polyps between 5 and 15 mm and its implications on surveillance. A prospective, multicenter study. (POPS study).Surgical endoscopy · 2022Article
- Artificial intelligence-assisted colonoscopy: A review of current state of practice and research.World journal of gastroenterology · 2021Review
- Sessile serrated lesion detection rates during average risk screening colonoscopy: A systematic review and meta-analysis of the published literature.Endoscopy international open · 2021Review
- Artificial intelligence-aided colonoscopy: Recent developments and future perspectives.World journal of gastroenterology · 2020Review
- Hyperplastic polyp or sessile serrated lesion? The contribution of serial sections to reclassification.Diagnostic pathology · 2020Article
- Evaluation of MALAT1 promoter DNA methylation patterns in early colorectal lesions and tumors.Gastroenterology and hepatology from bed to bench · 2019Article
- Colorectal Serrated Neoplasia: An Institutional 12-Year Review Highlights the Impact of a Screening Programme.Gastroenterology research and practice · 2019Article
- The Serrated Polyp Pathway: Is It Time to Alter Surveillance Guidelines?Current gastroenterology reports · 2017Review
- The clinical impact of serrated colorectal polyps.Clinical epidemiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecommended follow-up intervals after endoscopic removal of hyperplastic polyps (HP) and sessile serrated adenomas (SSA) differ because of assumed differences in biological behaviour. However, histopathologic differentiation is difficult, with higher SSA rates reported from specialist GI histopathologists.
objectiveThe objective of this study was to clarify the relevance of histologic reassessment of HP. DESIGN AND
settingFrom a prospective screening colonoscopy study relevant serrated lesions (excluding distal small HP ≤5 mm) diagnosed by private practice pathologists were reassessed by four specialized GI pathologists PATIENTS: One thousand sixty-nine screening colonoscopies were performed in patients. MAIN OUTCOME MEASUREMENTS: In terms of main outcome measurements, there is a likelihood of changes of the HP diagnosis on reassessment, as well as interrater variability.
resultsSSA were initially diagnosed in 7 cases (0.7%) and relevant HP in 83 (7.8%; 101 lesions). Of the latter, the chance of a change in diagnosis from HP to SSA by any of the four specialist histopathologists was higher for larger (>5 mm) and right-sided lesions (19.1 vs 1.3%, OR 18.4, p = 0.04) including a higher likelihood to change recommended follow-up intervals (32.1 vs 3.3%, p < 0.01). However, follow-up intervals were determined by concomitant adenomas in 41%. Interrater variability was also higher for these lesions (p = 0.04), with an overall kappa value of 0.48. However, this issue related to only 1.2% of the 1069 study cases. LIMITATION: The limitations this study are the limited case number as well as limited retrospective assessment.
conclusionsRight-sided HP >5 mm had a higher chance of change in diagnosis to SSA; therefore, they should probably be treated like adenomas and be removed. However, reliable data for recommendations on follow-up intervals of HP or SSA will require follow-up studies.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.