ArticleBMC public health2016
Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024.
Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Cardiovascular Disease Prognostic Models in Latin America and the Caribbean: A Systematic Review.Global heart · 2019Pooled it
- Cognitive impairment and hospital admission risk among community-dwelling adults in the MAUCO cohort.Annals of medicine · 2026Article
- Circulating amino acids and Type 2 diabetes in a Latin American population-based cohort.Cardiovascular diabetology · 2026Article
- Single-cell research in Latin America and the Caribbean builds genomics datasets for equitable AI-powered precision medicine.Nature reviews. Molecular cell biology · 2026Article
- Developing a non-invasive algorithm for the diagnosis of steatotic liver disease in primary healthcare: a retrospective cohort study.BMJ health & care informatics · 2025Article
- The Psychometric Properties of the ACE-IQ Questionnaire's Binary and Frequency Scoring Methods in a Chilean Community Sample.Children (Basel, Switzerland) · 2025Article
- Exposure to pesticides in Chile and its relationship with carcinogenic potential: a review.Frontiers in public health · 2025Review
- A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development.Biological research · 2024Article
- International prevalence patterns of low eGFR in adults aged 18-60 without traditional risk factors from population-based cross-sectional studies: a disadvantaged populations eGFR epidemiology (DEGREE) study.medRxiv : the preprint server for health sciences · 2024Article
- Sex disparities in gallstone disease: insights from the MAUCO prospective population-based cohort study.BMJ open gastroenterology · 2024Article
- Biobanks and data interoperability in Latin America: engendering high-quality evidence for the global research ecosystem.Frontiers in medicine · 2024Review
- Association between number of remaining teeth and incident depression in a rural Chilean cohort.BMC oral health · 2023Article
- High Burden of Intestinal Colonization With Antimicrobial-Resistant Bacteria in Chile: An Antibiotic Resistance in Communities and Hospitals (ARCH) Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Prevalence and Factors Associated with Subjective Memory Complaint in a Semi-Rural Community in Chile.Journal of Alzheimer's disease : JAD · 2023Article
- A preliminary study on aflatoxin exposure by urine biomonitoring in Chile.Mycotoxin research · 2022Article
- Air Pollution and Cardiorespiratory Changes in Older Adults Living in a Polluted Area in Central Chile.Environmental health insights · 2022Article
- Processed meat consumption and associated factors in Chile: A cross-sectional study nested in the MAUCO cohort.Frontiers in public health · 2022Article
- Article
- Assessment of Mycotoxin Exposure in a Rural County of Chile by Urinary Biomarker Determination.Toxins · 2021Article
- The Chile Biliary Longitudinal Study: A Gallstone Cohort.American journal of epidemiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundMaule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina´s population is of particular interest because in the last few decades it changed from being undernourished to suffering excess caloric intake, and it currently has the highest national rates of cardiovascular diseases, stomach cancer and gallbladder cancer. Between 2009 and 2011 Molina´s poverty rate dropped from 24.1 % to 13.5 % (national average 20.4 %); in this period the county went from insufficient to almost complete basic sanitation. Despite these advances, chemical pollutants in the food and air are increasing. Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases. METHODS/
designMAUCO is the core project of the recently established Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile & Pontificia Universidad Católica de Chile. In this study, we are enrolling and following 10,000 adults aged 38 to 74 years over 10 years. All eligible Molina residents will be enrolled. Participants were identified through a household census. Consenting individuals answer an epidemiological survey exploring risk factors (psycho-social, pesticides, diet, alcohol, and physical activity), medical history and physical and cognitive conditions; provide fasting blood, urine, and saliva samples; receive an electrocardiogram, abdominal ultrasound and bio-impedance test; and take a hand-grip strength test. These subjects will be re-interviewed after 2, 5 and 7 years. Active surveillance of health events is in place throughout the regional healthcare system. The MAUCO Bio-Bank will store 30 to 50 aliquots per subject using an NIH/NCI biorepository system for secure and anonymous linkage of samples with data. DISCUSSION: MAUCO´s results will help design public health interventions tailored to agricultural populations in Latin America.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.