Evidence map›Paper›PMID 26847432›Full record

SynthesisReviews in endocrine & metabolic disorders2015

Using systematic reviews for hazard and risk assessment of endocrine disrupting chemicals.

Anna Beronius, Laura N Vandenberg

Abstract readSystematic Review
In one paragraph

Synthesis in Reviews in endocrine & metabolic disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anna BeroniusDepartment of Environmental Science and Analytical Chemistry, Stockholm University, Stockholm, Sweden.
Laura N VandenbergDepartment of Environmental Health Sciences, University of Massachusetts Amherst School of Public Health & Health Sciences, 149B Goessmann, 686 N. Pleasant Street, Amherst, MA, 01003, USA. lvandenberg@schoolph.umass.edu.

Funding

Impact of Environmental Estrogens on Sexually Dimorphic Development of the Mouse Mammary GlandK22ES025811 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI VANDENBERG, LAURA N. · 2015 to 2017
$445k
NIEHS NIH HHS K22 ES025811NIEHS NIH HHS K22ES025811
6 · The paper itself

Abstract

The possibility that endocrine disrupting chemicals (EDCs) in our environment contribute to hormonally related effects and diseases observed in human and wildlife populations has caused concern among decision makers and researchers alike. EDCs challenge principles traditionally applied in chemical risk assessment and the identification and assessment of these compounds has been a much debated topic during the last decade. State of the science reports and risk assessments of potential EDCs have been criticized for not using systematic and transparent approaches in the evaluation of evidence. In the fields of medicine and health care, systematic review methodologies have been developed and used to enable objectivity and transparency in the evaluation of scientific evidence for decision making. Lately, such approaches have also been promoted for use in the environmental health sciences and risk assessment of chemicals. Systematic review approaches could provide a tool for improving the evaluation of evidence for decision making regarding EDCs, e.g. by enabling systematic and transparent use of academic research data in this process. In this review we discuss the advantages and challenges of applying systematic review methodology in the identification and assessment of EDCs.

Indexed as

Decision MakingEcosystemEndocrine DisruptorsEnvironmental PollutantsHumansRisk AssessmentEndocrine DisruptorsEnvironmental Pollutants(4–6): endocrine disruptorGuideline endpointHazard assessmentLow doseStudy evaluationThreshold

Identifiers

PMID26847432
PMCPMC4803521

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.