Evidence map›Paper›PMID 26847341›Full record

ArticleBMC infectious diseases2016

Chronological, geographical, and seasonal trends of human cases of avian influenza A (H5N1) in Vietnam, 2003-2014: a spatial analysis.

Toshie Manabe, Kazue Yamaoka, Toshiro Tango, Nguyen Gia Binh, Dao Xuan Co, Nguyen Dang Tuan, Shinyu Izumi, Jin Takasaki, Ngo Quy Chau, Koichiro Kudo

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
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  4. The COVID-19 Pandemic: Public Health and Epidemiology.Asia-Pacific journal of public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Toshie ManabeTeikyo University, Graduate School of Public Health, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. manabe@kklabo.gr.jp.
Kazue YamaokaTeikyo University, Graduate School of Public Health, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. kazue@med.teikyo-u.ac.jp.
Toshiro TangoTeikyo University, Graduate School of Public Health, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan. tango@medstat.jp.
Nguyen Gia BinhBach Mai Hospital, Intensive Care Unit, 78 Giai Phong, Dong Da, Hanoi, Vietnam. drbinhicu@gmail.com.
Dao Xuan CoBach Mai Hospital, Intensive Care Unit, 78 Giai Phong, Dong Da, Hanoi, Vietnam. daoxuanco@gmail.com.
Nguyen Dang TuanBach Mai Hospital, Intensive Care Unit, 78 Giai Phong, Dong Da, Hanoi, Vietnam. drtuan2004@yahoo.com.
Shinyu IzumiNational Center for Global Health and Medicine, Division of Pulmonary Medicine, Tokyo, Japan. izumis-tky@umin.ac.jp.
Jin TakasakiNational Center for Global Health and Medicine, Division of Pulmonary Medicine, Tokyo, Japan. jintakajj@gmail.com.
Ngo Quy ChauDepartment of Pulmonary Medicine, Bach Mai Hospital, 78 Giai Phong, Dong Da, Hanoi, Vietnam. ngoquychaubmh@gmail.com.
Koichiro KudoWaseda University, 1-21-1 Nishi-Waseda, Shinjuku-ku, Tokyo, Japan. kudo@kklabo.gr.jp.
Bạch Mai Hospital · VNTeikyo University · JPNational Center for Global Health and Medicine · JPWaseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman cases of highly pathogenic avian influenza A (H5N1) virus infection continue to occur in Southeast Asia. The objective of this study was to identify when and where human H5N1 cases have occurred in Vietnam and how the situation has changed from the beginning of the H5N1 outbreaks in 2003 through 2014, to assist with implementing methods of targeted disease management.

methodsWe assessed the disease clustering and seasonal variation of human H5N1 cases in Vietnam to evaluate the geographical and monthly timing trends. The clustering of H5N1 cases and associated mortality were examined over three time periods: the outbreak period (2003-2005), the post-outbreak (2006-2009), and the recent period (2010-2014) using the flexibly shaped space-time scan statistic. The most likely cases to co-cluster and the elevated risks for incidence and mortality were assessed via calculation of the relative risk (RR). The H5N1 case seasonal variation was analysed as the cyclic trend in incidence data using Roger's statistical test.

resultsBetween 2003 and 2005, H5N1 cases (RR: 2.15, p = 0.001) and mortality (RR: 2.49, p = 0.021) were significantly clustered in northern Vietnam. After 2010, H5N1 cases tended to occur on the border with Cambodia in the south, while H5N1 mortality clustered significantly in the Mekong delta area (RR: 6.62, p = 0.002). A significant seasonal variation was observed (p < 0.001), with a higher incidence of morbidity in December through April.

conclusionsThese findings indicate that clinical preparedness for H5N1 in Vietnam needs to be strengthened in southern Vietnam in December-April.

Indexed as

SeasonsAsia, SoutheasternCambodiaClimateCluster AnalysisDisease OutbreaksGeographyHumansIncidenceInfluenza A Virus, H5N1 SubtypeInfluenza, HumanSurvival AnalysisTime FactorsVietnam

Identifiers

PMID26847341
PMCPMC4743110
OpenAlexW2269033061

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.