Evidence map›Paper›PMID 26847340›Full record

ArticleAMB Express2016

Combining glucose and sodium acetate improves the growth of Neochloris oleoabundans under mixotrophic conditions.

Helder Rodrigues Silva, Cassio Egidio Cavenaghi Prete, Freddy Zambrano, Victor Hugo de Mello, Cesar Augusto Tischer, Diva Souza Andrade

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 48 citations in OpenAlex.

  1. Integrated Production of Microalgal Oil fromFoods (Basel, Switzerland) · 2026
    Article
  2. Impact ofBiotechnologia · 2024
    Article
  3. Influence of Carbon Sources on Biomass and Biomolecule Accumulation inInternational journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Helder Rodrigues SilvaDept of Agronomy, Universidade Estadual de Londrina, Londrina, Paraná, 86051900, Brazil.
Cassio Egidio Cavenaghi PreteDept of Agronomy, Universidade Estadual de Londrina, Londrina, Paraná, 86051900, Brazil.
Freddy ZambranoDept of Agronomy, Universidade Estadual de Londrina, Londrina, Paraná, 86051900, Brazil.
Victor Hugo de MelloCollege of Chemistry, Universidade Norte do Paraná, Londrina, Paraná, 86041120, Brazil.
Cesar Augusto TischerDept of Biotechnology, Universidade Estadual de Londrina, Londrina, Paraná, 86051990, Brazil.
Diva Souza AndradeInstituto Agronômico do Paraná, CP 480, Londrina, Paraná, 86.047-902, Brazil. diva@iapar.br.
Instituto Agronômico do Paraná · BRUniversidade Estadual de Londrina · BRUniversidade Norte do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixotrophic cultivation is a potential approach to produce microalgal biomass that can be used as raw materials for renewable biofuels and animal feed, although using a suitable, cost-effective organic carbon source is crucial. Here, we used a Box-Behnken design with three factors, the glucose and sodium acetate concentrations, and the percentage of Bold's basal medium (BBM), to evaluate the effects of different carbon sources on biomass productivity and the protein and lipid contents of Neochloris oleoabundans (UTEX#1185). When grow at optimal levels of these factors, 100 % BBM plus 7.5 g L(-1) each of glucose and sodium acetate, N. oleoabundans yielded 1.75 g L(-1) of dry biomass, with 4.88 ± 0.09 % N, 24.01 ± 0.29-30.5 ± 0.38 % protein, and 34.4 % ± 0.81 lipids. A nuclear magnetic resonance spectrum ((1)H-NMR) of a lipid extract showed that the free fatty acid content was 11.25 %. Thus, combining glucose and sodium acetate during the mixotrophic cultivation of N. oleoabundans can yield greater amounts of biomass, proteins, and lipids for biofuel production.

Indexed as

BBM dilutionFree fatty acidMixotrophicResponse surface methodologyTotal lipidTotal protein

Identifiers

PMID26847340
PMCPMC4816098
OpenAlexW2274808576

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.