Evidence map›Paper›PMID 26847290›Full record

Trial reportYonsei medical journal2016

Percutaneous Coronary Intervention Is More Beneficial Than Optimal Medical Therapy in Elderly Patients with Angina Pectoris.

Hoyoun Won, Ae Young Her, Byeong Keuk Kim, Yong Hoon Kim, Dong Ho Shin, Jung Sun Kim, Young Guk Ko, Donghoon Choi, Hyuck Moon Kwon, Yangsoo Jang and 1 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Yonsei medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Hoyoun WonCardiovascular and Arrhythmia Center, College of Medicine, Chung-Ang University, Seoul, Korea.
Ae Young HerDepartment of Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea.
Byeong Keuk KimDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Yong Hoon KimDepartment of Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea.
Dong Ho ShinDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Jung Sun KimDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Young Guk KoDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Donghoon ChoiDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Hyuck Moon KwonDivision of Cardiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Yangsoo JangDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University Health System, Seoul, Korea.
Myeong Ki HongCardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Yonsei University Health System · KRKangwon National University · KRYonsei University · KRChung-Ang University · KRGangnam Severance Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeData comparing the clinical benefits of medical treatment with those of percutaneous coronary intervention (PCI) in an elderly population with angina pectoris are limited. Therefore, we evaluated the efficacy of elective PCI versus optimal medical treatment (OMT) in elderly patients (between 75 and 84 years old) with angina pectoris. MATERIALS AND

methodsOne hundred seventy-seven patients with significant coronary artery stenosis were randomly assigned to either the PCI group (n=90) or the OMT group (n=87). The primary outcome was a composite of major adverse events in the 1-year follow-up period that included cardiovascular death, non-fatal myocardial infarction, coronary revascularization, and stroke.

resultsMajor adverse events occurred in 5 patients (5.6%) of the PCI group and in 17 patents (19.5%) of the OMT group (p=0.015). There were no significant differences between the PCI group and the OMT group in cardiac death [hazard ratio (HR) for the PCI group 0.454; 95% confidence interval (CI) 0.041-5.019, p=0.520], myocardial infarction (HR 0.399; 95% CI 0.039-4.050, p=0.437), or stroke (HR 0.919; 95% CI 0.057-14.709, p=0.952). However, the PCI group showed a significant preventive effect of the composite of major adverse events (HR 0.288; 95% CI 0.106-0.785, p=0.015) and against the need for coronary revascularization (HR 0.157; 95% CI 0.035-0.703, p=0.016).

conclusionElective PCI reduced major adverse events and was found to be an effective treatment modality in elderly patients with angina pectoris and significant coronary artery stenosis, compared to OMT.

Indexed as

Percutaneous Coronary InterventionAgedAged, 80 and overAngina PectorisCoronary StenosisFemaleHumansMaleMyocardial InfarctionProportional Hazards ModelsProspective StudiesRepublic of KoreaStrokeTreatment Outcomeangina pectoriselderly patientPercutaneous coronary intervention

Identifiers

PMID26847290
PMCPMC4740530
OpenAlexW2264418345

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.