ArticleInternational orthopaedics2016
Risk profile of patients developing nonunion of the clavicle and outcome of treatment--analysis of fifty five nonunions in seven hundred and twenty nine consecutive fractures.
Article in International orthopaedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06652659 (Risk Factors for Development of Non-union of Displaced Midshaft Clavicle Fractures), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors for Development of Non-union of Displaced Midshaft Clavicle Fractures: A Prospective Double-center Cohort Study
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Therapeutic effect of autologous bone grafting with adjuvant bone morphogenetic protein on long bone nonunion: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2022Pooled it
- Overtreatment of displaced midshaft clavicle fractures.Acta orthopaedica · 2016Trial
- The role of patient and surgeon characteristics on the treatment decision for displaced midshaft clavicle fractures in athletes: a global survey.JSES reviews, reports, and techniques · 2026Article
- Minimally invasive plate osteosynthesis (MIPO) with mini-open technique versus open reduction and internal fixation (ORIF) in the treatment of displaced midclavicular fracture: a retrospective study.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025Article
- Outcomes of conservatively treated midshaft clavicle fractures with butterfly fragment.Joint diseases and related surgery · 2025Article
- Article
- [Clavicle nonunion].Unfallchirurgie (Heidelberg, Germany) · 2024Article
- Predictors requiring special attention to prevent clavicle fracture nonunion: a systematic review of literature.Trauma surgery & acute care open · 2023Article
- Plate fixation of midshaft clavicle fractures for delayed union and non-union is a cost-effective intervention but functional deficits persist at long-term follow-up.Shoulder & elbow · 2022Article
- Safe and Effective Treatment of Compromised Clavicle Fracture of the Medial and Lateral Third Using Focused Shockwaves.Journal of clinical medicine · 2022Article
- Low-intensity extracorporeal shock wave therapy for midshaft clavicular delayed union: A case report and review of literature.World journal of clinical cases · 2021Article
- Clavicle fractures in adults; current concepts.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Review
- Medial Femoral Condyle Vascularized Bone Graft for Treatment of Midshaft Clavicle Recalcitrant Nonunion With Use of the Transverse Cervical Artery as an Anastomosis.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020Article
- Surgical approach for open reduction and internal fixation of clavicle fractures: a comparison of vertical and horizontal incisions.International orthopaedics · 2019Article
- Clavicle fracture nonunion in the paediatric population: a systematic review of the literature.Journal of children's orthopaedics · 2018Article
- [Intramedullary nailing in diaphyseal clavicle fractures using minimally invasive percutaneous reduction].Operative Orthopadie und Traumatologie · 2017Review
- Comparative study suggests that human bone morphogenetic proteins have no influence on the outcome of operative treatment of aseptic clavicle non-unions.International orthopaedics · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe most common complication following treatment of a clavicle fracture is nonunion. Most nonunions are symptomatic and treatment is mostly operative. The aim of this study was to describe risk profiles of patients developing nonunion and what outcome is observed following operative treatment of clavicle nonunions.
methodsIn a consecutive series of 729 clavicle fractures we retrospectively identified 55 that developed nonunion (49 diaphysial and six lateral). All were treated operatively by reconstruction with (n = 28) or without (n = 27) autologous bone graft. Assessment of functionality and patient reported satisfaction and remission of symptoms was done a minimum of six months post-operatively by mail. Response rate was 60%.
resultsThe overall nonunion rate was 7.5%. Nine nonunions were initially treated operatively. Risk factors associated with nonunion of our series was anatomic site, fracture complexity, female gender, smoking habits and initial treatment. A total of eight post-operative complications were found. Remission of symptoms was reported by 29 of the 33. Outright satisfaction with current shoulder condition was reported by 24. The overall median DASH was 8 (range 0-61). Following revision of the eight complications a total of 53 united successfully.
conclusionOperative treatment of a clavicular nonunion seems to be effective as most patients unite and experience remission of symptoms. However, complications in close to 15% and lack of satisfaction of approximately 27% have to be acknowledged and thoroughly explained to the patient prior to treatment.
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