Evidence map›Paper›PMID 26847065›Full record

ArticleBlood2016

Collagen binding to OSCAR: the odd couple.

Bo An, Barbara Brodsky

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Inhibitory pattern recognition receptors.The Journal of experimental medicine · 2022
    Review
  2. Impact of Vimentin on Regulation of Cell Signaling and Matrix Remodeling.Frontiers in cell and developmental biology · 2022
    Review
  3. Prokaryotic Collagen-Like Proteins as Novel Biomaterials.Frontiers in bioengineering and biotechnology · 2022
    Review
  4. Collagen Mimetic Peptides.Bioengineering (Basel, Switzerland) · 2021
    Review
  5. Targeted Drug Delivery via the Use of ECM-Mimetic Materials.Frontiers in bioengineering and biotechnology · 2020
    Review
  6. Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases.Frontiers in cell and developmental biology · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Bo AnTUFTS UNIVERSITY.ORCID http://orcid.org/0000-0002-1031-3380
Barbara BrodskyTUFTS UNIVERSITY.ORCID http://orcid.org/0000-0002-3889-8763

Funding

Stuctural studies of triple-helical proteinsR01GM060048 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRODSKY, BARBARA M · 1999 to 2016
$5.1M
Biomaterial Applications of Recombinant Bacterial CollagensR01EB011620 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI BRODSKY, BARBARA M, KAPLAN, DAVID L. · 2010 to 2013
$1.3M
NIBIB NIH HHS R01 EB011620NIGMS NIH HHS R01 GM060048
6 · The paper itself

Abstract

In this issue of Blood, Zhou et al reported the high-resolution structure of the collagen-activated osteoclast-associated receptor (OSCAR) bound to a collagen model peptide. Together with binding studies, the results confirm a novel recognition mechanism for collagen by immunoglobulin-like motifs.

Indexed as

CollagenHumansReceptors, Cell SurfaceCollagenReceptors, Cell Surface

Identifiers

PMID26847065
PMCPMC4742544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.