ArticleChronic respiratory disease2016
Preclinical lung disease in early rheumatoid arthritis.
Article in Chronic respiratory disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The prevalence and risk factors of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis.Annals of medicine · 2024Pooled it
- Prevalence and risk factors of bronchiectasis in rheumatoid arthritis: A systematic review and meta-analysis.Seminars in arthritis and rheumatism · 2021Pooled it
- A causal relationship between rheumatoid arthritis and bronchiectasis? A systematic review and meta-analysis.Chronic respiratory diseasePooled it
- Association of Plasma miRNA-7-5p and miRNA-214-5p With Rheumatoid Arthritis Associated Interstitial Lung Disease.International journal of rheumatic diseases · 2026Article
- DNA from Slow-Growing Mycobacteria in Culture Negative Sputa Reveal Common Exposure to Mycobacteria.Biology · 2026Article
- The prevalence of interstitial lung disease and bronchiectasis in rheumatoid arthritis: A systematic review and meta-analysis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Screening for rheumatoid arthritis-associated interstitial lung disease using low-dose CT: an emerging approach - an observational prospective case-control study.Arthritis research & therapy · 2025Observational
- Four-factor risk score for the prediction of interstitial lung disease in rheumatoid arthritis.Rheumatology international · 2023Article
- Photon-counting computed tomography in the assessment of rheumatoid arthritis-associated interstitial lung disease: an initial experienceDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease.Arthritis & rheumatology (Hoboken, N.J.) · 2022Article
- Rheumatoid arthritis-associated interstitial lung disease: an overview of epidemiology, pathogenesis and management.Clinical rheumatology · 2021Review
- Is bronchiectasis really a disease?European respiratory review : an official journal of the European Respiratory Society · 2020Article
- Association of rheumatoid arthritis-related autoantibodies with pulmonary function test abnormalities in a rheumatoid arthritis registry.Clinical rheumatology · 2019Article
- Interstitial Lung Disease in Rheumatoid Arthritis Remains a Challenge for Clinicians.Journal of clinical medicine · 2019Review
- Interstitial lung abnormalities in patients with early rheumatoid arthritis: A pilot study evaluating prevalence and progression.European journal of rheumatology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early detection and treatment of lung disease in patients with rheumatoid arthritis (RA) may ameliorate disease progression. The objectives of this study were to investigate the frequency of asymptomatic lung abnormalities in early RA patients and the potential association of positive RA blood reactive biomolecules with lung involvement. A prospective observational study was performed in a cohort of patients with early RA (joint symptoms < 2 years) without respiratory symptoms, who were included in a screening program for lung disease with a baseline chest radiograph (CR) and complete pulmonary function tests (PFTs). In those patients with lung abnormalities on the CR or PFTs, a high-resolution chest computed tomography scan (HRCT) was performed. We included 40 patients (30 women). Altered PFTs were detected in 18 (45%) of these patients. These cases had a diffusion lung transfer capacity of carbon monoxide (DLCO) of <80% of predicted, without a significant reduction in the forced vital capacity. The HRCT detected abnormalities in 11 of the 18 patients. Diffuse bronchiectasis was the main finding. An inverse correlation between the anti-citrullinated peptide antibody (ACPA) levels and DLCO was found. Asymptomatic lung disease is present in up to 45% of early RA patients and can be determined by PFTs and ACPA levels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.