Evidence map›Paper›PMID 26846369›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Characterization of attenuation and respiratory motion artifacts and their influence on SPECT MP image evaluation using a dynamic phantom assembly with variable cardiac defects.

Isabelle Chrysanthou-Baustert, Irene Polycarpou, Ourania Demetriadou, Lefteris Livieratos, Antonis Lontos, Antonis Antoniou, Stelios Christofides, Charalambos Yiannakkaras, Demetris Kaolis, Christoforos Panagidis and 2 more

Abstract readEvaluation Study
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Anthropomorphic cardiac phantom for dynamic SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  5. A moving liver phantom in an anthropomorphic thorax for SPECT MP imaging.Physical and engineering sciences in medicine · 2022
    Article
  6. A new cardiac phantom for dynamic SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  7. Inter-reader variability of SPECT MPI readings in low- and middle-income countries: Results from the IAEA-MPI Audit Project (I-MAP).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  8. Have SPECT artifacts breathed their last?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Isabelle Chrysanthou-BaustertFrederick Research Center, Nicosia, Cyprus. isabelle.chrysanthou@gmail.com.
Irene PolycarpouDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Ourania DemetriadouDepartment of Nuclear Medicine, Limassol General Hospital, Limassol, Cyprus.
Lefteris LivieratosDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Antonis LontosFrederick Research Center, Nicosia, Cyprus.
Antonis AntoniouFrederick Research Center, Nicosia, Cyprus.
Stelios ChristofidesDepartment of Medical Physics, Nicosia General Hospital, Nicosia, Cyprus.
Charalambos YiannakkarasDepartment of Medical Physics, Nicosia General Hospital, Nicosia, Cyprus.
Demetris KaolisDepartment of Medical Physics, Nicosia General Hospital, Nicosia, Cyprus.
Christoforos PanagidisDepartment of Nuclear Medicine, Nicosia General Hospital, Nicosia, Cyprus.
Paul K MarsdenDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Yiannis ParpottasFrederick Research Center, Nicosia, Cyprus. yparpottas@frederick.ac.cy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA phantom assembly that simulates the respiratory motion of the heart was used to investigate artifacts and their impact on defect detection.

methodsSPECT/CT images were acquired for phantoms with and without small and large cardiac defects during normal and deep breathing, and also at four static respiratory phases. Acquisitions were reconstructed with and without AC, and with misalignment of transmission and emission scans. A quantitative analysis was performed to assess artifacts. Two physicians reported on defect presence or absence and their results were evaluated.

resultsAll large defects were correctly reported. Attenuation reduced uptake in the basal LV walls, increasing FN physicians' reports for small defects. Respiratory motion reduced uptake mainly in the anterior and inferior walls increasing FP and FN reports on images without and with small defects, respectively. Artifacts due to misalignment between CT and SPECT scans in normal breathing phantoms did not influence the physicians' reports.

conclusionsAttenuation and respiratory motion correction should be applied to reduce artifacts before reporting on small defects in deep breathing conditions. Artifacts due to misalignment between CT and SPECT scans do not affect defect detection in normal breathing when the LV is co-registered in SPECT and CT images prior to AC.

Indexed as

ArtifactsPhantoms, ImagingRespiratory MechanicsEquipment DesignEquipment Failure AnalysisHeart DiseasesHumansImage EnhancementImage Interpretation, Computer-AssistedMotionMyocardial Perfusion ImagingReproducibility of ResultsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonAttenuation and respiratory motion artifactsCardiac defectsCardiac motion due to respirationSPECT/CT MPI

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.