ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017
Accuracy of myocardial perfusion imaging in detecting multivessel coronary artery disease: A cardiac CZT study.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic performance of myocardial perfusion imaging with conventional and CZT single-photon emission computed tomography in detecting coronary artery disease: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Diagnostic Effect of Attenuation Correction in Myocardial Perfusion Imaging in Different Coronary Arteries: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- Detecting Triple-Vessel Disease with Cadmium Zinc Telluride-Based Single-Photon Emission Computed Tomography Using the Intensity Signal-to-Noise Ratio between Rest and Stress Studies.Contrast media & molecular imaging · 2017Trial
- Prognostic Significance of Dynamic CZT Cardiac-Dedicated SPECT-derived Myocardial Flow Reserve in Patients with Suspected or Confirmed Coronary Artery Disease and Normal Myocardial PerfusionCurrent medical imaging · 2026Article
- Editorial: Case reports in cardiovascular imaging 2023.Frontiers in cardiovascular medicine · 2024Article
- Coronary physiology in the cath lab: is "virtual FFR" ready for the prime time?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Lung-to-heart ratio analysis using virtual planar images obtained from myocardial perfusion SPECT data: A phantom and clinical studies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The diagnostic value of SPECT CZT quantitative myocardial blood flow in high-risk patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Dynamic ultrafast CZT imaging: Time for a paradigm change in myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Capabilities of Modern Semiconductor Gamma Cameras in Radionuclide Diagnosis of Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Myocardial stress perfusion scintigraphy for outcome prediction in patients with severe left ventricular systolic dysfunction.European journal of nuclear medicine and molecular imaging · 2021Article
- Effects of gender and defect reversibility on detection of coronary disease with an upright and supine cadmium-zinc-telluride camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Changes in left ventricle myocardial volume during stress test using cadmium-zinc-telluride cardiac imaging: Implications in coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Triglyceride-glucose index predicts outcome in patients with chronic coronary syndrome independently of other risk factors and myocardial ischaemia.European heart journal open · 2021Article
- Head-to-head comparison of a CZT-based all-purpose SPECT camera and a dedicated CZT cardiac device for myocardial perfusion and functional analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- MPI in the era of CZT cameras: Absolute numbers are still better than relative figures.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020Review
- Left ventricular eccentricity index measured with SPECT myocardial perfusion imaging: An additional parameter of adverse cardiac remodeling.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras.European journal of hybrid imaging · 2019Article
- Interactions between myocardial sympathetic denervation and left ventricular mechanical dyssynchrony: A CZT analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial perfusion imaging (MPI) performed on traditional single-photon emission computed-tomography cameras has been shown to have a sub-optimal accuracy in detecting multivessel coronary artery disease (CAD).
methodsSix-hundred and ninety-five patients were submitted to MPI on a novel cadmium-zinc-telluride (CZT) camera and coronary angiography. A coronary stenosis >70% was considered obstructive. In every patient, the summed stress score (SSS) was computed. Moreover, the regional stress scores were also calculated for every coronary territory.
resultsFour-hundred and forty-one patients had obstructive CAD in one (28%), two (19%), or three (17%) vessels. At per-patient analysis, the SSS showed a significant accuracy in detecting obstructive CAD (AUC 0.87, P < .001). Specifically, its accuracy was maintained also in patients with double (AUC 0.83; P < .001) or triple-vessels disease (AUC 0.79, P < .001), where CZT was able to correctly identify CAD extent in 64% of patients. On a per-vessel basis, CZT confirmed its high accuracy in detecting obstructive CAD (AUC 0.88, P < .001), independently from the involved coronary vessel.
conclusionsMPI performed on a CZT camera is highly accurate in detecting obstructive CAD, independently from the coronary artery involved and the overall disease burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.