ArticleBMC microbiology2016
Population structure and associated phenotypes of Salmonella enterica serovars Derby and Mbandaka overlap with host range.
Article in BMC microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Characterization and Antimicrobial Resistance of Non-TyphoidalMicroorganisms · 2025Article
- A multi-country outbreak ofEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Detection ofPathogens (Basel, Switzerland) · 2024Article
- Genotypic and phenotypic analysis ofFrontiers in microbiology · 2024Article
- Phenotypic and genomic characterization ofMicrobial genomics · 2023Article
- Incidence and Genomic Background of Antibiotic Resistance in Food-Borne and Clinical Isolates ofAntibiotics (Basel, Switzerland) · 2023Article
- Geography shapes the genomics and antimicrobial resistance of Salmonella enterica Serovar Enteritidis isolated from humans.Scientific reports · 2023Article
- Characterization of nontyphoidalFrontiers in cellular and infection microbiology · 2023Article
- Prophage-mediated genome differentiation of theMicrobial genomics · 2022Article
- Prevalence, Characterization, and Pathogenicity ofAnimals : an open access journal from MDPI · 2021Article
- Population Biology and Comparative Genomics of Campylobacter Species.Current topics in microbiology and immunology · 2021Review
- Municipal Wastewater Surveillance Revealed a High Community Disease Burden of a Rarely Reported and Possibly SubclinicalApplied and environmental microbiology · 2020Article
- Population structure ofF1000Research · 2020Article
- Source Attribution Study of SporadicFrontiers in microbiology · 2020Article
- Identifying emerging trends in antimicrobial resistance using Salmonella surveillance data in poultry in Spain.Transboundary and emerging diseases · 2020Article
- Pathogenic potential of non-typhoidal Salmonella serovars isolated from aquatic environments in Mexico.Genes & genomics · 2019Article
- Genetic Diversity ofPathogens (Basel, Switzerland) · 2019Article
- Characterization of ciprofloxacin-resistant and ESBL-producing Salmonella enteric serotype Derby in Eastern China.BMC microbiology · 2019Article
- Population genomics of bacterial host adaptation.Nature reviews. Genetics · 2018Review
- Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10.Cell reports · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe Salmonella enterica serovar Derby is frequently isolated from pigs and turkeys whereas serovar Mbandaka is frequently isolated from cattle, chickens and animal feed in the UK. Through comparative genomics, phenomics and mutant construction we previously suggested possible mechanistic reasons why these serovars demonstrate apparently distinct host ranges. Here, we investigate the genetic and phenotypic diversity of these two serovars in the UK. We produce a phylogenetic reconstruction and perform several biochemical assays on isolates of S. Derby and S. Mbandaka acquired from sites across the UK between the years 2000 and 2010.
resultsWe show that UK isolates of S. Mbandaka comprise of one clonal lineage which is adapted to proficient utilisation of metabolites found in soya beans under ambient conditions. We also show that this clonal lineage forms a biofilm at 25 °C, suggesting that this serovar maybe well adapted to survival ex vivo, growing in animal feed. Conversely, we show that S. Derby is made of two distinct lineages, L1 and L2. These lineages differ genotypically and phenotypically, being divided by the presence and absence of SPI-23 and the ability to more proficiently invade porcine jejunum derived cell line IPEC-J2.
conclusionThe results of this study lend support to the hypothesis that the differences in host ranges of S. Derby and S. Mbandaka are adaptations to pathogenesis, environmental persistence, as well as utilisation of metabolites abundant in their respective host environments.
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