ArticleScientific reports2016
Multimodality hard-x-ray imaging of a chromosome with nanoscale spatial resolution.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 57 citations in OpenAlex.
- Development and testing of a dual-frequency real-time hardware feedback system for the hard X-ray nanoprobe beamline of the SSRF.Journal of synchrotron radiation · 2025Article
- Towards routine 3D characterization of intact mesoscale samples by multi-scale and multimodal scanning X-ray tomography.Scientific reports · 2022Article
- Off-axis multilayer zone plate with 16 nm × 28 nm focus for high-resolution X-ray beam induced current imaging.Journal of synchrotron radiation · 2021Article
- Contribution of advanced fluorescence nano microscopy towards revealing mitotic chromosome structure.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Review
- X-ray Ptychography Imaging of Human Chromosomes After Low-dose Irradiation.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- Micromachined Silicon Platform for Precise Assembly of 2D Multilayer Laue Lenses for High-Resolution X-ray Microscopy.Micromachines · 2020Article
- Cryo-nanoscale chromosome imaging-future prospects.Biophysical reviews · 2020Review
- Article
- Multimodal x-ray and electron microscopy of the Allende meteorite.Science advances · 2019Article
- X-ray Fluorescence Nanotomography of Single Bacteria with a Sub-15 nm Beam.Scientific reports · 2018Article
- Nanospectroscopy Captures Nanoscale Compositional Zonation in Barite Solid Solutions.Scientific reports · 2018Article
- Microscopy Instrumentation and Nanopositioning at NSLS-II: Current Status and Future Directions.Synchrotron radiation news · 2018Article
- Ellipsoidal mirror for two-dimensional 100-nm focusing in hard X-ray region.Scientific reports · 2017Article
- Rapid alignment of nanotomography data using joint iterative reconstruction and reprojection.Scientific reports · 2017Article
- Nanoscale measurement of trace element distributions in Spartina alterniflora root tissue during dormancy.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed a scanning hard x-ray microscope using a new class of x-ray nano-focusing optic called a multilayer Laue lens and imaged a chromosome with nanoscale spatial resolution. The combination of the hard x-ray's superior penetration power, high sensitivity to elemental composition, high spatial-resolution and quantitative analysis creates a unique tool with capabilities that other microscopy techniques cannot provide. Using this microscope, we simultaneously obtained absorption-, phase-, and fluorescence-contrast images of Pt-stained human chromosome samples. The high spatial-resolution of the microscope and its multi-modality imaging capabilities enabled us to observe the internal ultra-structures of a thick chromosome without sectioning it.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.