Evidence map›Paper›PMID 26846121›Full record

ReviewObesity surgery2016

Insulinoma After Bariatric Surgery: Diagnostic Dilemma and Therapeutic Approaches.

Christopher M Mulla, Alessandra Storino, Eric U Yee, David Lautz, Mandeep S Sawnhey, A James Moser, Mary-Elizabeth Patti

Abstract readReview
In one paragraph

Review in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Insulinoma after sleeve gastrectomy: A case report.World journal of clinical cases · 2022
    Article
  6. Article
  7. Postbariatric hypoglycemia: symptom patterns and associated risk factors in the Longitudinal Assessment of Bariatric Surgery study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021
    Article
  8. [Quality of indications in bariatric surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
  9. Review
  10. Review
  11. Review
  12. Hypoglycemia After Gastric Bypass Surgery: Current Concepts and Controversies.The Journal of clinical endocrinology and metabolism · 2018
    Review
  13. Article
  14. Review
  15. Observational
  16. Medical nutrition therapy for post-bariatric hypoglycemia: practical insights.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017
    Review
  17. Diagnosis and Management of Post-Bariatric Hypoglycemia.Journal of the American Board of Family Medicine : JABFM
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher M MullaResearch Division, Joslin Diabetes Center, 1 Joslin Place, Boston, MA, 02215, USA.
Alessandra StorinoHarvard Medical School, Boston, MA, USA.
Eric U YeeHarvard Medical School, Boston, MA, USA.
David LautzHarvard Medical School, Boston, MA, USA.
Mandeep S SawnheyHarvard Medical School, Boston, MA, USA.
A James MoserHarvard Medical School, Boston, MA, USA.
Mary-Elizabeth PattiResearch Division, Joslin Diabetes Center, 1 Joslin Place, Boston, MA, 02215, USA. mary.elizabeth.patti@joslin.harvard.edu.

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
TRAINING IN DIABETES AND METABOLISMT32DK007260 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$13.6M
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS T32 DK007260
6 · The paper itself

Abstract

Hypoglycemia is increasingly recognized as a complication of bariatric surgery. Typically, hypoglycemia does not appear immediately postoperatively, but rather more than 1 year later, and usually occurs 1-3 h after meals. While rare, insulinoma has been reported after bariatric surgery. Clinical factors which should raise suspicion for insulinoma and the need for comprehensive clinical and biochemical evaluation include hypoglycemia occurring in the fasting state, predating bariatric surgery, and/or worsening immediately postoperatively, and lack of response to conservative therapy. Localization and successful resection of insulinoma can be achieved using novel endoscopic ultrasound and surgical approaches. In summary, hypoglycemia presenting shortly after gastric bypass or with a dominant fasting pattern should be fully evaluated to exclude insulinoma. Additionally, evaluation prior to gastric bypass should include screening for history of hypoglycemia symptoms.

Indexed as

Bariatric SurgeryHumansHypoglycemiaInsulinomaObesity, MorbidPancreatic NeoplasmsPostoperative PeriodBariatric surgeryGastric bypassHypoglycemiaInsulinomaMinimally invasive surgery

Identifiers

PMID26846121
PMCPMC4814298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.