Evidence map›Paper›PMID 26845698›Full record

ArticleFish & shellfish immunology2016

Proteomic analysis by iTRAQ in red claw crayfish, Cherax quadricarinatus, hematopoietic tissue cells post white spot syndrome virus infection.

Joseph Jeswin, Xiao-lu Xie, Qiao-lin Ji, Ke-jian Wang, Hai-peng Liu

Abstract read
In one paragraph

Article in Fish & shellfish immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Proteomic Analysis of the Hemolymph AfterFrontiers in immunology · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph JeswinState Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361102, Fujian, PR China.
Xiao-lu XieState Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361102, Fujian, PR China.
Qiao-lin JiState Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361102, Fujian, PR China.
Ke-jian WangState Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361102, Fujian, PR China; Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Fujian Engineering Laboratory of Marine Bioproducts and Technology, Xiamen 361102, Fujian, PR China.
Hai-peng LiuState Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361102, Fujian, PR China; Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Fujian Engineering Laboratory of Marine Bioproducts and Technology, Xiamen 361102, Fujian, PR China. Electronic address: haipengliu@xmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To elucidate proteomic changes of Hpt cells from red claw crayfish, Cherax quadricarinatus, we have carried out isobaric tags for relative and absolute quantitation (iTRAQ) of cellular proteins at both early (1 hpi) and late stage (12 hpi) post white spot syndrome virus (WSSV) infection. Protein database search revealed 594 protein hits by Mascot, in which 17 and 30 proteins were present as differentially expressed proteins at early and late viral infection, respectively. Generally, these differentially expressed proteins include: 1) the metabolic process related proteins in glycolysis and glucogenesis, DNA replication, nucleotide/amino acid/fatty acid metabolism and protein biosynthesis; 2) the signal transduction related proteins like small GTPases, G-protein-alpha stimulatory subunit, proteins bearing PDZ- or 14-3-3-domains that help holding together and organize signaling complexes, casein kinase I and proteins of the MAP-kinase signal transduction pathway; 3) the immune defense related proteins such as α-2 macroglobulin, transglutaminase and trans-activation response RNA-binding protein 1. Taken together, these protein information shed new light on the host cellular response against WSSV infection in a crustacean cell culture.

Indexed as

AnimalsArthropod ProteinsAstacoideaHematopoietic SystemProteomicsSequence Analysis, DNAWhite spot syndrome virus 1Arthropod ProteinsCrayfish hematopoietic tissue cellsiTRAQProteomicsWhite spot syndrome virus

Identifiers

PMID26845698
PMCPMC7111676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.