ArticleNPJ primary care respiratory medicine2016
TOTALL: high cost of allergic rhinitis-a national Swedish population-based questionnaire study.
Article in NPJ primary care respiratory medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
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Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.
- Multiple acupuncture and moxibustion therapies for allergic rhinitis in adults: a network Meta-analysis of randomized controlled trials.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Pooled it
- Limited beneficial effects of systemic steroids when added to standard of care treatment of seasonal allergic rhinitis.Scientific reports · 2023Trial
- Intralymphatic immunotherapy with birch and grass pollen extracts. A randomized double-blind placebo-controlled clinical trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023Trial
- Intralymphatic immunotherapy with one or two allergens renders similar clinical response in patients with allergic rhinitis due to birch and grass pollen.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Trial
- Trial
- The Impact of Allergic Rhinitis on Australian Adults in an Urban Setting: A Qualitative Exploration.Journal of clinical medicine · 2026Article
- The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection.World journal of otorhinolaryngology - head and neck surgery · 2026Review
- Article
- Efficacy of Montelukast-Antihistamine Combination Therapy Versus Antihistamine Monotherapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis.Clinical and experimental otorhinolaryngology · 2026Article
- Individual and Societal Economic Burden of Chronic Rhinosinusitis with or Without Nasal Polyps.Medical sciences (Basel, Switzerland) · 2026Article
- Allergen-specific human IgE isolated through an allergen-agnostic pipeline-understanding immune response and allergen recognition.Communications biology · 2026Article
- Potential of real-time pollen data: perceived needs and symptom management among seasonal allergic rhinitis patients.Frontiers in allergy · 2026Article
- The nasal-oral microbiome axis in allergic rhinitis: environmental triggers, microbial dysbiosis, and immune dysregulation.Frontiers in allergy · 2026Review
- [Current status and progress of health economics research on allergen specific immunotherapy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Review
- Real-world efficacy of sublingual immunotherapy with Japanese cedar pollen for cypress pollinosis.The journal of allergy and clinical immunology. Global · 2025Article
- Clinical Practice and Outcome of Septoplasty-A Retrospective Study of 11,714 Surgeries in Sweden 2014-2023.Laryngoscope investigative otolaryngology · 2025Article
- The Severity of Pollen-Induced Allergic Rhinitis at 16 Years of Age: Data From the Population-Based BAMSE Birth Cohort.Allergy · 2025Article
- Observational
- ARIA-Italy managing allergic rhinitis and asthma in a changing world: The role of the Pharmacist.The World Allergy Organization journal · 2025Review
- Integrated bioinformatics analysis of biomarkers and pathways to explore the mechanisms and molecular targets related to allergic rhinitis and pyroptosis.Scientific reports · 2025Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic rhinitis is a global illness with a well-recognised impact on quality of life and work performance. Comparatively little is known about the extent of its economic impact on society. The TOTALL study estimates the total cost of allergic rhinitis using a sample representing the entire Swedish population of working age. A questionnaire focused on allergic rhinitis was mailed out to a random population of Swedish residents, aged 18-65 years. Health-care contacts, medications, absenteeism (absence from work) and presenteeism (reduced working capacity at work) were assessed, and the direct and indirect costs of allergic rhinitis were calculated. Medication use was evaluated in relation to the ARIA guidelines. In all, 3,501 of 8,001 (44%) answered the questionnaire, and 855 (24%) of these reported allergic rhinitis. The mean annual direct and indirect costs because of allergic rhinitis were €210.3 and €750.8, respectively, resulting in a total cost of €961.1 per individual/year. Presenteeism represented 70% of the total cost. Antihistamines appear to be used in excess in relation to topical steroids, and the use of nasal decongestants was alarmingly high. The total cost of allergic rhinitis in Sweden, with a population of 9.5 million, was estimated at €1.3 billion annually. These unexpectedly high costs could be related to the high prevalence of disease, in combination with the previously often underestimated indirect costs. Improved adherence to guidelines might ease the economic burden on society.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.