SynthesisDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2016
Self-expanding metal stents for acute refractory esophageal variceal bleeding: A systematic review and meta-analysis.
Synthesis in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 63 citations in OpenAlex.
- Endoscopic management of acute esophagogastric variceal bleeding: recent advances.Therapeutic advances in gastroenterology · 2026Review
- Stents and Emerging Alternatives in Upper Gastrointestinal Endoscopy: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Decline of the Sengstaken-Blakemore tube: A review of shifting practices in gastrointestinal hemorrhage management.World journal of critical care medicine · 2025Review
- Endoscopic Variceal Therapy With Multisystemic Glue Embolism: A Case Report and Narrative Review of a Rare but Severe Complication.Case reports in critical care · 2025Article
- Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Treatment of Bleeding from Cardiofundal and Ectopic Varices in Cirrhosis.Journal of clinical medicine · 2024Review
- Article
- Article
- [Gastrointestinal bleeding in old age].Zeitschrift fur Gerontologie und Geriatrie · 2024Article
- Managing liver cirrhotic complications: Overview of esophageal and gastric varices.Clinical and molecular hepatology · 2020Review
- Endoscopic Ultrasound-Guided, Percutaneous, and Transjugular Liver Biopsy: A Comparative Systematic Review and Meta-Analysis.Clinical endoscopy · 2020Article
- Self-expanding metal stents versus TIPS in treatment of refractory bleeding esophageal varices: a systematic review and meta-analysis.Endoscopy international open · 2020Article
- Efficacy and safety of EUS-guided gastroenterostomy for benign and malignant gastric outlet obstruction: a systematic review and meta-analysis.Endoscopy international open · 2019Article
- Outcomes after placement of a SX-ELLA oesophageal stent for refractory variceal bleeding-A national multicentre study.Liver international : official journal of the International Association for the Study of the Liver · 2019Article
- Update on the management of gastrointestinal varices.World journal of gastrointestinal pharmacology and therapeutics · 2019Review
- A simplified technique of esophageal self-expandable metallic stent placement without fluoroscopic and endoscopic guidance for treating esophageal carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2018Article
- Management of Refractory Variceal Bleed in Cirrhosis.Journal of clinical and experimental hepatologyReview
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimEsophageal variceal bleeding is a severe complication of portal hypertension with significant morbidity and mortality. A substantial portion of cirrhotics fail to respond to conventional medical therapy and band ligation, necessitating alternative treatments including self-expanding metal stent (SEMS) placement for acute refractory esophageal variceal bleeding. In the present study, we carried out a systematic review and structured meta-analysis of all eligible studies to evaluate the technical feasibility, safety, clinical efficacy, and survival advantage of SEMS placement for the treatment of of acute esophageal variceal bleeding.
methodsSearches of PubMed, EMBASE, Web of Science, and the Cochrane Library databases were carried out through December 2015. Individual study proportions were transformed into a quantity using the Freeman-Tukey variant of the arcsine square root transformed proportion. Combined weighted proportions, and meta-regression were then determined.
resultsThe search yielded 12 studies involving n = 155 patients included in our meta-analysis. Pooled clinical success rate in achieving hemostasis within 24 h was 96% (95% CI, 0.90-1.00). Technical success for SEMS deployment endoscopically was achieved in 97% of patients (95% CI, 0.91-1.00). Total adverse events (including rebleeding after 48 h, ulceration, and stent migration) were shown in 36% of patients after SEMS placement (95% CI, 0.23-0.50). Pooled 30-day and 60-day survival rates were 68% (95% CI, 0.56-0.80) and 64% (95% CI, 0.48-0.78), respectively.
conclusionThis study demonstrated that esophageal SEMS placement is a technically feasible modality and highly efficacious in achieving hemostasis in acute esophageal variceal hemorrhage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.