ReviewCurrent opinion in endocrinology, diabetes, and obesity2016
Advancing methods for US transgender health research.
Review in Current opinion in endocrinology, diabetes, and obesity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 3 syntheses or guidelines pooled it, 177 citations in OpenAlex.
- Health status of transgender people globally: A systematic review of research on disease burden and correlates.PloS one · 2024Pooled it
- Antiandrogen or estradiol treatment or both during hormone therapy in transitioning transgender women.The Cochrane database of systematic reviews · 2020Pooled it
- Current research gaps: a global systematic review of HIV and sexually transmissible infections among transgender populations.Sexual health · 2017Pooled it
- Efficacy, safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir for HIV pre-exposure prophylaxis in transgender women: a secondary analysis of the HPTN 083 trial.The lancet. HIV · 2023Trial
- Stigma and HIV service access among transfeminine and gender diverse women in South Africa - a narrative analysis of longitudinal qualitative data from the HPTN 071 (PopART) trial.BMC public health · 2020Trial
- Plasma and intracellular pharmacokinetics of tenofovir disoproxil fumarate and emtricitabine in transgender women receiving feminizing hormone therapy.The Journal of antimicrobial chemotherapy · 2020Trial
- Special Issue: New Horizons in HIV and Reproductive Health Research: HIV Acquisition and Reproductive Health in Key Populations.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
- A scoping review of models to identify transgender patients in electronic health records.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Perceived safety and trust shape transgender and gender diverse participation in exercise science: a consensual qualitative research study.Frontiers in sports and active living · 2026Article
- Kidney Health and Gender-Affirming Hormone Therapy for Transgender and Gender Diverse Individuals.Clinical journal of the American Society of Nephrology : CJASN · 2026Review
- Global Perspectives on HPV Vaccination: Achievements, Challenges, and Lessons from the Brazilian Experience.Vaccines · 2025Review
- Ethical considerations for conducting research with transgender and gender-diverse patient registries: Balancing our need for evidence with patient vulnerability.Journal of public health research · 2025Article
- Incident Atherosclerotic Cardiovascular Disease Among Veterans by Gender Identity: A Cohort Study.Journal of general internal medicine · 2025Article
- Article
- Stratified analysis of health and gender-affirming care among Italian transgender and gender diverse adults.Journal of endocrinological investigation · 2025Article
- Comparing two-step approaches to measuring gender identity: the reliability and applications of asking about sex assigned at birth vs transgender self-identification.American journal of epidemiology · 2025Article
- Acceptability of an organ inventory for cancer screening across gender identity and intersex status.Journal of the National Cancer Institute · 2025Article
- Mental Health during Medical Transition in a US and Canadian Sample of Early Socially Transitioned Transgender Youth.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Validating a Case Definition for Transgender Adults Using Administrative Data.JAMA network open · 2025Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 13 institutions in 3 countries.
Funding
Abstract
purpose of reviewThis article describes methodological challenges, gaps, and opportunities in US transgender health research. RECENT
findingsLack of large prospective observational studies and intervention trials, limited data on risks and benefits of sex affirmation (e.g., hormones and surgical interventions), and inconsistent use of definitions across studies hinder evidence-based care for transgender people. Systematic high-quality observational and intervention-testing studies may be carried out using several approaches, including general population-based, health systems-based, clinic-based, venue-based, and hybrid designs. Each of these approaches has its strength and limitations; however, harmonization of research efforts is needed. Ongoing development of evidence-based clinical recommendations will benefit from a series of observational and intervention studies aimed at identification, recruitment, and follow-up of transgender people of different ages, from different racial, ethnic, and socioeconomic backgrounds and with diverse gender identities. SUMMARY: Transgender health research faces challenges that include standardization of lexicon, agreed upon population definitions, study design, sampling, measurement, outcome ascertainment, and sample size. Application of existing and new methods is needed to fill existing gaps, increase the scientific rigor and reach of transgender health research, and inform evidence-based prevention and care for this underserved population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.