ArticlePloS one2016
Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Long-term outcomes of coronary artery bypass grafting versus stent-PCI for unprotected left main disease: a meta-analysis.BMC cardiovascular disorders · 2017Pooled it
- Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial.Journal of the American Heart Association · 2024Trial
- Trial
- Gender Differences in Survival after Coronary Artery Bypass Grafting-13-Year Results from KROK Registry.Journal of clinical medicine · 2024Article
- Sex differences in outcomes of patients undergoing on-pump coronary artery bypass grafting surgery.PloS one · 2024Observational
- Investigation of Combined Carotid Endarterectomy and Coronary Artery Bypass Graft Surgery Outcomes and Adverse Event Risk Factors in the Vascular Quality Initiative.Vascular and endovascular surgery · 2023Article
- Female gender does not have any significant impact on the early postoperative outcomes after coronary artery bypass grafting: a propensity-matched analysis.Indian journal of thoracic and cardiovascular surgery · 2023Article
- Effect of Gender on Postoperative Outcome and Duration of Ventilation After Coronary Artery Bypass Grafting (CABG).Cureus · 2023Article
- Long-Term Patency of Venous Conduits Targeting the Right Coronary Artery System-Single Is Superior to Sequential bypass Grafting.Journal of cardiovascular development and disease · 2022Article
- Do in-hospital outcomes of isolated coronary artery bypass grafting vary between male and female octogenarians?Interactive cardiovascular and thoracic surgery · 2022Article
- Incidence and Outcomes of Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting of a Randomized Controlled Trial: A Blinded End-of-cycle Analysis.Reviews in cardiovascular medicine · 2022Article
- Impact of gender on 10-year outcome after coronary artery bypass grafting.Interactive cardiovascular and thoracic surgery · 2021Article
- Does Age Affect the Short- and Long-Term Outcomes of Coronary Bypass Grafting?The International journal of angiology : official publication of the International College of Angiology, Inc · 2021Review
- Sex differences in mortality in stable patients undergoing vasodilator stress cardiovascular magnetic resonance.Open heart · 2021Article
- Neointimal Hyperplasia after Carotid Transection and Anastomosis Surgery is Associated with Degradation of Decorin and Platelet Derived Growth Factor Signaling.JVS-vascular science · 2021Article
- Sex Differences in Long-Term Survival After Major Cardiac Surgery: A Population-Based Cohort Study.Journal of the American Heart Association · 2019Article
- Current trends in selection of conduits for coronary artery bypass grafting.General thoracic and cardiovascular surgery · 2017Review
- Minimally invasive coronary artery bypass as a safe method of surgical revascularization. The step towards hybrid procedures.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2017Article
- Article
- Are the Early Postoperative Outcomes of Coronary Artery Bypass Grafting Surgery in Elderly Women Worse Compared to Men's?Brazilian journal of cardiovascular surgeryObservational
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFemale gender is a known risk factor for early and late mortality after coronary artery bypass graft surgery (CABG). Higher age of women at operation may influence outcome, since age per se is also an important risk factor. The purpose of our study was to analyze possible gender differences in outcome after isolated CABG in different age groups to delineate the impact of female gender and age.
methodsAll patients over 60 years of age undergoing isolated CABG at our department during 2001 and 2011 were included and categorized by age into sexagenarians (2266, 16.6% women), septuagenarians (2332, 25.4% women) and octogenarians (374, 32% women) and assessed by gender for 30-day and 180-day mortality.
resultsThirty-day mortality was significantly higher in women only amongst septuagenarians (7.1 vs. 4.7%, p = 0.033). Same differences apply for 180-day mortality (12.3 vs. 8.2%, p = 0.033) and estimated one-year survival (81.6 ± 4.2 vs. 86.9 ± 2.2%, p = 0.001). Predictive factors for 30-day mortality of septuagenarian were logistic EuroSCORE (ES) (p = 0.003), perioperative myocardial infarction (MI) (p<0.001), pneumonia (p<0.001), abnormal LV-function (p<0.04) and use of LIMA graft (p<0.001), but not female gender. However, female gender was found to be an independent predictor for 180-day mortality (HR 1.632, p = 0.001) in addition to ES, use of LIMA graft, perioperative MI, pneumonia and abnormal LV function (HR 1.013, p = 0.004; HR 0.523, p<0.001; HR 2.710, p<0.001; HR 3.238, p<0.001; HR 2.013, p<0.001).
conclusionWomen have a higher observed probability of early death after CABG in septuagenarians. However, female gender was not found to be an independent risk factor for 30-day, but for 180-day survival. Therefore, reduction of high impact risk factors such as perioperative MI and enhancement of LIMA use should be future goals. In view of our findings, decision for surgical revascularization should not be based on gender.
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