ArticlePLoS neglected tropical diseases2016
Current Perspectives on Plague Vector Control in Madagascar: Susceptibility Status of Xenopsylla cheopis to 12 Insecticides.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Experimental evidence of early-phase transmission of Yersinia pestis by Synopsyllus fonquerniei and Xenopsylla brasiliensis.PLoS neglected tropical diseases · 2026Article
- Plagued by the Past, Pressed by the Present: A One Health Perspective onBiomedicines · 2025Review
- Opportunities and challenges for plague vector control in Madagascar.PLoS neglected tropical diseases · 2025Review
- Insecticide Resistance of Xenopsylla cheopis in Madagascar: Revision of Diagnostic Doses for Bioassay and Exploration of Biochemical Mechanisms.The American journal of tropical medicine and hygiene · 2025Article
- Knowledge and practices related to plague persistence in plague-endemic foci, Mbulu District, Tanzania.PLoS neglected tropical diseases · 2024Article
- Reproductive ecology of the black rat (Rattus rattus) in Madagascar: the influence of density-dependent and -independent effects.Integrative zoology · 2024Article
- Knockdown resistance mutations are common and widely distributed in Xenopsylla cheopis fleas that transmit plague in Madagascar.PLoS neglected tropical diseases · 2023Article
- Assessing the effectiveness of intervention to prevent plague through community and animal-based survey.PLOS global public health · 2023Article
- Emerging rodent-associated Bartonella: a threat for human health?Parasites & vectors · 2022Review
- Exploring and Mitigating Plague for One Health Purposes.Current tropical medicine reports · 2022Article
- Factors influencing the re-emergence of plague in Madagascar.Emerging topics in life sciences · 2020Review
- Human plague: An old scourge that needs new answers.PLoS neglected tropical diseases · 2020Review
- An Evaluation of the Flea Index as a Predictor of Plague Epizootics in the West Nile Region of Uganda.Journal of medical entomology · 2020Article
- First detection of the kdr mutation (L1014F) in the plague vector Xenopsylla cheopis (Siphonaptera: Pulicidae).Parasites & vectors · 2019Article
- Field assessment of insecticide dusting and bait station treatment impact against rodent flea and house flea species in the Madagascar plague context.PLoS neglected tropical diseases · 2019Article
- Trends of Human Plague, Madagascar, 1998-2016.Emerging infectious diseases · 2019Article
- Plague risk in vulnerable community: assessment of Xenopsylla cheopis susceptibility to insecticides in Malagasy prisons.Infectious diseases of poverty · 2017Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plague is a rodent disease transmissible to humans by infected flea bites, and Madagascar is one of the countries with the highest plague incidence in the world. This study reports the susceptibility of the main plague vector Xenopsylla cheopis to 12 different insecticides belonging to 4 insecticide families (carbamates, organophosphates, pyrethroids and organochlorines). Eight populations from different geographical regions of Madagascar previously resistant to deltamethrin were tested with a World Health Organization standard bioassay. Insecticide susceptibility varied amongst populations, but all of them were resistant to six insecticides belonging to pyrethroid and carbamate insecticides (alphacypermethrin, lambdacyhalothrin, etofenprox, deltamethrin, bendiocarb and propoxur). Only one insecticide (dieldrin) was an efficient pulicide for all flea populations. Cross resistances were suspected. This study proposes at least three alternative insecticides (malathion, fenitrothion and cyfluthrin) to replace deltamethrin during plague epidemic responses, but the most efficient insecticide may be different for each population studied. We highlight the importance of continuous insecticide susceptibility surveillance in the areas of high plague risk in Madagascar.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.