Evidence map›Paper›PMID 26843983›Full record

ArticleAnemia2015

The Cost-Effectiveness of Continuous Erythropoiesis Receptor Activator Once Monthly versus Epoetin Thrice Weekly for Anaemia Management in Chronic Haemodialysis Patients.

Omar Maoujoud, Samir Ahid, Hocein Dkhissi, Zouhair Oualim, Yahia Cherrah

Open access · goldAbstract read
In one paragraph

Article in Anemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Omar MaoujoudResearch Team of Pharmacoepidemiology & Pharmacoeconomics, Medical and Pharmacy School, Mohammed V University, Madinat Al Irfane, 10000 Rabat, Morocco; Department of Nephrology & Dialysis, Military Hospital Agadir, 20450 Agadir, Morocco.
Samir AhidResearch Team of Pharmacoepidemiology & Pharmacoeconomics, Medical and Pharmacy School, Mohammed V University, Madinat Al Irfane, 10000 Rabat, Morocco.
Hocein DkhissiMeknes Dialysis Center (on Behalf of Moroccan Society of Nephrology), 33150 Meknes, Morocco.
Zouhair OualimIdrissAlakbar Dialysis Center (on Behalf of the Scientific Committee, Moroccan Society of Nephrology), 12470 Rabat, Morocco.
Yahia CherrahResearch Team of Pharmacoepidemiology & Pharmacoeconomics, Medical and Pharmacy School, Mohammed V University, Madinat Al Irfane, 10000 Rabat, Morocco.
Mohammed V University · MAMoroccan Foundation for Advanced Science, Innovation and Research · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. The aim of this study was to compare the cost-effectiveness of continuous erythropoietin receptor activator (CERA) once monthly to epoetin beta (EpoB) thrice weekly to maintain haemoglobin (Hb) within the range 10.5-12 g/dL. Methods. Prospective cohort study and cost-effectiveness analysis. Chronic haemodialysis patients (CHP), being treated with EpoB, were selected for two periods of follow-up: period 1, maintaining prior treatment with EpoB, and period 2, conversion to CERA once monthly. Hb concentrations and costs were measured monthly. Health care payer perspective for one year was adopted. Results. 75 CHP completed the study, with a mean age of 52.9 ± 14.3 years. Baseline Hb was 11.14 ± 1.18 g/dL in EpoB phase and 11.46 ± 0.79 g/dL in CERA phase; we observed a significant increase in the proportion of patients successfully treated (Hb within the recommended range), 65.3% versus 70.7%, p: 0.008, and in the average effectiveness by 4% (0.55 versus 0.59). Average cost-effectiveness ratios were 6013.86 and 5173.64$, with an ICER CERA to EpoB at -6457.5$. Conclusion. Our health economic evaluation of ESA use in haemodialysis patients suggests that the use of CERA is cost-effective compared with EpoB.

Identifiers

PMID26843983
PMCPMC4710935
OpenAlexW2272589190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.