ArticleJournal of neurophysiology2016
Neural correlates of behavioral amplitude modulation sensitivity in the budgerigar midbrain.
Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Hierarchical transformations in sound envelope encoding differ across cortical layers.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Interareal and interlaminar differences in sound envelope encoding in core and parabelt auditory cortex.bioRxiv : the preprint server for biology · 2025Article
- Article
- Precise spike-timing information in the brainstem is well aligned with the needs of communication and the perception of environmental sounds.PLoS biology · 2025Article
- Forward masking of amplitude modulation: Sensory versus perceptual components.The Journal of the Acoustical Society of America · 2025Article
- Hierarchical differences in the encoding of amplitude modulation in the subcortical auditory system of awake nonhuman primates.Journal of neurophysiology · 2024Article
- Neurometric amplitude modulation detection in the inferior colliculus of Young and Aged rats.Hearing research · 2024Article
- Normal behavioral discrimination of envelope statistics in budgerigars with kainate-induced cochlear synaptopathy.Hearing research · 2024Article
- Histological Correlates of Auditory Nerve Injury from Kainic Acid in the Budgerigar (Melopsittacus undulatus).Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Mechanisms of masking by Schroeder-phase harmonic tone complexes in the budgerigar (Melopsittacus undulatus).Hearing research · 2023Article
- Animal models of hidden hearing loss: Does auditory-nerve-fiber loss cause real-world listening difficulties?Molecular and cellular neurosciences · 2022Review
- Midbrain-Level Neural Correlates of Behavioral Tone-in-Noise Detection: Dependence on Energy and Envelope Cues.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Intracortical Microelectrode Array Unit Yield under Chronic Conditions: A Comparative Evaluation.Micromachines · 2021Review
- Effects of Kainic Acid-Induced Auditory Nerve Damage on Envelope-Following Responses in the Budgerigar (Melopsittacus undulatus).Journal of the Association for Research in Otolaryngology : JARO · 2021Article
- Normal Tone-In-Noise Sensitivity in Trained Budgerigars despite Substantial Auditory-Nerve Injury: No Evidence of Hidden Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Animal Models of Tinnitus Treatment: Cochlear and Brain Stimulation.Current topics in behavioral neurosciences · 2021Article
- Identifying cues for tone-in-noise detection using decision variable correlation in the budgerigar (Melopsittacus undulatus).The Journal of the Acoustical Society of America · 2020Article
- Effects of selective auditory-nerve damage on the behavioral audiogram and temporal integration in the budgerigar.Hearing research · 2019Article
- Amplitude Modulation Detection in Children with a History of Temporary Conductive Hearing Loss Remains Impaired for Years After Restoration of Normal Hearing.Journal of the Association for Research in Otolaryngology : JARO · 2019Article
- Persistent Auditory Nerve Damage Following Kainic Acid Excitotoxicity in the Budgerigar (Melopsittacus undulatus).Journal of the Association for Research in Otolaryngology : JARO · 2018Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Amplitude modulation (AM) is a crucial feature of many communication signals, including speech. Whereas average discharge rates in the auditory midbrain correlate with behavioral AM sensitivity in rabbits, the neural bases of AM sensitivity in species with human-like behavioral acuity are unexplored. Here, we used parallel behavioral and neurophysiological experiments to explore the neural (midbrain) bases of AM perception in an avian speech mimic, the budgerigar (Melopsittacus undulatus). Behavioral AM sensitivity was quantified using operant conditioning procedures. Neural AM sensitivity was studied using chronically implanted microelectrodes in awake, unrestrained birds. Average discharge rates of multiunit recording sites in the budgerigar midbrain were insufficient to explain behavioral sensitivity to modulation frequencies <100 Hz for both tone- and noise-carrier stimuli, even with optimal pooling of information across recording sites. Neural envelope synchrony, in contrast, could explain behavioral performance for both carrier types across the full range of modulation frequencies studied (16-512 Hz). The results suggest that envelope synchrony in the budgerigar midbrain may underlie behavioral sensitivity to AM. Behavioral AM sensitivity based on synchrony in the budgerigar, which contrasts with rate-correlated behavioral performance in rabbits, raises the possibility that envelope synchrony, rather than average discharge rate, might also underlie AM perception in other species with sensitive AM detection abilities, including humans. These results highlight the importance of synchrony coding of envelope structure in the inferior colliculus. Furthermore, they underscore potential benefits of devices (e.g., midbrain implants) that evoke robust neural synchrony.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.