ArticleBiology letters2016
Conjugation is necessary for a bacterial plasmid to survive under protozoan predation.
Article in Biology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- Bacterivorous CiliateAntibiotics (Basel, Switzerland) · 2025Article
- Tetrahymena predation drives adaptive evolution of Salmonella by disrupting O-antigen biosynthesis and upregulating transcriptional regulator csgD.The ISME journal · 2025Article
- Protozoa-enhanced conjugation frequency alters the dissemination of soil antibiotic resistance.The ISME journal · 2025Article
- Impact of Predation by CiliateAntibiotics (Basel, Switzerland) · 2024Article
- Ecological dynamics of plasmid transfer and persistence in microbial communities.Current opinion in microbiology · 2022Review
- Plasmid Viability Depends on the Ecological Setting of Hosts within a Multiplasmid Community.Microbiology spectrum · 2022Article
- Microbial warfare in the wild-the impact of protists on the evolution and virulence of bacterial pathogens.International microbiology : the official journal of the Spanish Society for Microbiology · 2021Review
- Indirect Selection against Antibiotic Resistance via Specialized Plasmid-Dependent Bacteriophages.Microorganisms · 2021Article
- Group II intron as cold sensor for self-preservation and bacterial conjugation.Nucleic acids research · 2020Article
- Evolution in interacting species alters predator life-history traits, behaviour and morphology in experimental microbial communities.Proceedings. Biological sciences · 2020Article
- Predator coevolution and prey trait variability determine species coexistence.Proceedings. Biological sciences · 2019Article
- Cheating, facilitation and cooperation regulate the effectiveness of phage-encoded exotoxins as antipredator molecules.MicrobiologyOpen · 2019Article
- Ecology determines how low antibiotic concentration impacts community composition and horizontal transfer of resistance genes.Communications biology · 2018Article
- Release and Constancy of an Antibiotic Resistance Gene in Seawater under Grazing Stress by Ciliates and Heterotrophic Nanoflagellates.Microbes and environments · 2017Article
- Antibiotic resistance in the wild: an eco-evolutionary perspective.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Horizontal gene transfer by conjugative plasmids plays a critical role in the evolution of antibiotic resistance. Interactions between bacteria and other organisms can affect the persistence and spread of conjugative plasmids. Here we show that protozoan predation increased the persistence and spread of the antibiotic resistance plasmid RP4 in populations of the opportunist bacterial pathogen Serratia marcescens. A conjugation-defective mutant plasmid was unable to survive under predation, suggesting that conjugative transfer is required for plasmid persistence under the realistic condition of predation. These results indicate that multi-trophic interactions can affect the maintenance of conjugative plasmids with implications for bacterial evolution and the spread of antibiotic resistance genes.
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