ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Time to Colonoscopy after Positive Fecal Blood Test in Four U.S. Health Care Systems.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed, 4 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Pooled it
- Second-generation capsule endoscopy for the detection of colorectal polyps: An updated systematic review and comparative meta-analysis of prospective studies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Pooled it
- Timely follow-up of positive cancer screening results: A systematic review and recommendations from the PROSPR Consortium.CA: a cancer journal for clinicians · 2018Pooled it
- Interventions to Improve Follow-up of Positive Results on Fecal Blood Tests: A Systematic Review.Annals of internal medicine · 2017Pooled it
- Time to Follow-Up Colonoscopy After Positive Fecal Immunochemical Test with Centralized Patient Navigation: A Randomized Clinical Trial.Journal of general internal medicine · 2026Trial
- Trial
- Prospective Cohort study of Predictors of Follow-Up Diagnostic Colonoscopy from a Pragmatic Trial of FIT Screening.Scientific reports · 2020Trial
- Is the patient activation measure associated with adherence to colonoscopy after a positive fecal occult blood test result?Israel journal of health policy research · 2018Trial
- Trial
- Inverse Association Between Regional Availability of Board-Certified Fellows of the Japan Gastroenterological Endoscopy Society and Colorectal Cancer Mortality in Japan: An Ecological Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Rates and Timing of Follow-up Colonoscopy After a Positive Stool-Based Test in an Integrated Health System.Journal of general internal medicine · 2026Article
- System-Wide Implementation of Colorectal Cancer Screening in a Value-Based Care Setting.Journal of general internal medicine · 2026Observational
- Adherence to Follow-Up Colonoscopy After a Positive Stool-Based Test in Patients Aged 45-49 Years: Real-World Differences Between Multitarget Stool DNA Testing and Fecal Immunochemical or Fecal Occult Blood Testing.Gastro hep advances · 2025Article
- Patterns of Care Following a Positive Fecal Blood Test for Colorectal Cancer: A Mixed Methods Study.Journal of general internal medicine · 2024Article
- Optimizing tracking and completion of follow-up colonoscopy after abnormal stool tests at health systems participating in the Centers for Disease Control and Prevention's Colorectal Cancer Control Program.Cancer causes & control : CCC · 2024Article
- Fecal Immunochemical Test Screening and Risk of Colorectal Cancer Death.JAMA network open · 2024Article
- Development of a Follow-Up Measure to Ensure Complete Screening for Colorectal Cancer.JAMA network open · 2024Observational
- Commentary: Health disparities across the cancer care continuum and implications for microsimulation modeling.Journal of the National Cancer Institute. Monographs · 2023Article
- Reach and effectiveness of a centralized navigation program for patients with positive fecal immunochemical tests requiring follow-up colonoscopy.Preventive medicine reports · 2023Article
- Rates of Follow-up Colonoscopy After a Positive Stool-Based Screening Test Result for Colorectal Cancer Among Health Care Organizations in the US, 2017-2020.JAMA network open · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo reduce colorectal cancer mortality, positive fecal blood tests must be followed by colonoscopy.
methodsWe identified 62,384 individuals ages 50 to 89 years with a positive fecal blood test between January 1, 2011 and December 31, 2012 in four health care systems within the Population-Based Research Optimizing Screening through Personalized Regimens (PROSPR) consortium. We estimated the probability of follow-up colonoscopy and 95% confidence intervals (CI) using the Kaplan-Meier method. Overall differences in cumulative incidence of follow-up across health care systems were assessed with the log-rank test. HRs and 95% CIs were estimated from multivariate Cox proportional hazards models.
resultsMost patients who received a colonoscopy did so within 6 months of their positive fecal blood test, although follow-up rates varied across health care systems (P <0.001). Median days to colonoscopy ranged from 41 (95% CI, 40-41) to 174 (95% CI, 123-343); percent followed-up by 12 months ranged from 58.1% (95% CI, 51.6%-63.7%) to 83.8% (95% CI, 83.4%-84.3%) and differences across health care systems were also observed at 1, 2, 3, and 6 months. Increasing age and comorbidity score were associated with lower follow-up rates.
conclusionIndividual characteristics and health care system were associated with colonoscopy after positive fecal blood tests. Patterns were consistent across health care systems, but proportions of patients receiving follow-up varied. These findings suggest that there is room to improve follow-up of positive colorectal cancer screening tests. IMPACT: Understanding the timing of colonoscopy after positive fecal blood tests and characteristics associated with lack of follow-up may inform future efforts to improve follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.