Evidence map›Paper›PMID 26843385›Full record

ArticleJournal of neurovirology2016

Overexpression of thyroid hormone receptor β1 altered thyroid hormone-mediated regulation of herpes simplex virus-1 replication in differentiated cells.

Feng Chen, Robert W Figliozzi, Gautam Bedadala, Jayavardhana Palem, S Victor Hsia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurovirology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Receipt of thyroid hormone deficiency treatment and risk of herpes zoster.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2017
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Feng ChenDepartment of Pharmaceutical Sciences, School of Pharmacy and Health Professions, University of Maryland Eastern Shore, Princess Anne, MD, USA.
Robert W FigliozziDepartment of Pharmaceutical Sciences, School of Pharmacy and Health Professions, University of Maryland Eastern Shore, Princess Anne, MD, USA.
Gautam BedadalaDepartment of Pharmaceutical Sciences, School of Pharmacy and Health Professions, University of Maryland Eastern Shore, Princess Anne, MD, USA.
Jayavardhana PalemDepartment of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA, USA.
S Victor HsiaDepartment of Pharmaceutical Sciences, School of Pharmacy and Health Professions, University of Maryland Eastern Shore, Princess Anne, MD, USA. vhsia@umes.edu.
University of Maryland Eastern Shore · USUniversity of Louisiana at Monroe · US

Funding

REGULATION OF HSV-1 GENE EXPRESSION AND REPLICATION BY NUCLEAR HORMONE RECEPTORS-Research SupplementR01NS081109 · NINDS · UNIVERSITY OF MARYLAND EASTERN SHORE · PI HSIA, SHAOCHUNG VICTOR · 2012 to 2016
$794k
NINDS NIH HHS R01 NS081109
6 · The paper itself

Abstract

Thyroid hormone (T

Indexed as

Host-Pathogen InteractionsAnimalsCell DifferentiationCell Line, TumorChlorocebus aethiopsEpithelial CellsGene DosageGene Expression RegulationGenes, ReporterGenetic EngineeringGreen Fluorescent ProteinsHerpesvirus 1, HumanImmediate-Early ProteinsNeuronsThyroid Hormone Receptors betaTriiodothyronineGreen Fluorescent ProteinsImmediate-Early ProteinsThyroid Hormone Receptors betaTriiodothyronineUbiquitin-Protein LigasesVmw110 protein, Human herpesvirus 1DifferentiationHerpes simplex virusNeuronsPlaque assayThyroid hormoneThyroid hormone receptor beta 1

Identifiers

PMID26843385
PMCPMC4972698
OpenAlexW2310886123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.