ArticleScientific reports2016
Exploring Carbon Nanomaterial Diversity for Nucleation of Protein Crystals.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Nucleation of protein crystals in pores and their growth.Biophysical reviews · 2025Review
- A generic cross-seeding approach to protein crystallization.Journal of applied crystallography · 2025Article
- Crystallisation and characterisation of muscle proteins: a mini-review.Journal of muscle research and cell motility · 2023Review
- Preparation and Characterization of Metal-Organic Framework Coatings for Improving Protein Crystallization Screening.Nanomaterials (Basel, Switzerland) · 2023Article
- Platinum deposition on functionalised graphene for corrosion resistant oxygen reduction electrodes.Journal of materials chemistry. A · 2022Article
- Article
- Ultrafast synthesis of carbon quantum dots from fenugreek seeds using microwave plasma enhanced decomposition: application of C-QDs to grow fluorescent protein crystals.Scientific reports · 2020Article
- Protein crystal structure determination with the crystallophore, a nucleating and phasing agent.Journal of applied crystallography · 2019Article
- Harnessing heterogeneous nucleation to control tin orientations in electronic interconnections.Nature communications · 2017Article
- Can the propensity of protein crystallization be increased by using systematic screening with metals?Protein science : a publication of the Protein Society · 2017Review
- Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence.Chemical science · 2017Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Controlling crystal nucleation is a crucial step in obtaining high quality protein crystals for structure determination by X-ray crystallography. Carbon nanomaterials (CNMs) including carbon nanotubes, graphene oxide, and carbon black provide a range of surface topographies, porosities and length scales; functionalisation with two different approaches, gas phase radical grafting and liquid phase reductive grafting, provide routes to a range of oligomer functionalised products. These grafted materials, combined with a range of controls, were used in a large-scale assessment of the effectiveness for protein crystal nucleation of 20 different carbon nanomaterials on five proteins. This study has allowed a direct comparison of the key characteristics of carbon-based nucleants: appropriate surface chemistry, porosity and/or roughness are required. The most effective solid system tested in this study, carbon black nanoparticles functionalised with poly(ethylene glycol) methyl ether of mean molecular weight 5000, provides a novel highly effective nucleant, that was able to induce crystal nucleation of four out of the five proteins tested at metastable conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.