ArticleMedical physics2016
A combined time-of-flight and depth-of-interaction detector for total-body positron emission tomography.
Article in Medical physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- optiGAN: a deep learning-based alternative to optical photon tracking in Python-based GATE (10+).Physics in medicine and biology · 2025Article
- Depth-of-interaction encoding techniques for pixelated PET detectors enabled by machine learning methods and fast waveform digitization.Physics in medicine and biology · 2025Article
- A Time-Walk and Timing-Shift Correction Method for Dual-Ended Readout TOF-DOI PET Detectors.IEEE transactions on radiation and plasma medical sciences · 2025Article
- PET detectors with depth-of-interaction and time-of-flight capabilities.Radiological physics and technology · 2024Review
- High-resolution Imaging Using Virtual-Pinhole PET Concept.PET clinics · 2024Review
- Performance evaluation of the PennPET explorer with expanded axial coverage.Physics in medicine and biology · 2023Article
- High-resolution and high-sensitivity PET for quantitative molecular imaging of the monoaminergic nuclei: A GATE simulation study.Medical physics · 2022Article
- Opportunities for Molecular Imaging in Multiple Sclerosis Management: Linking Probe to Treatment.Radiology · 2022Review
- Performance of Dual-Ended Readout PET Detectors Based on BGO Arrays and BaSOIEEE transactions on radiation and plasma medical sciences · 2022Article
- Multiplexed imaging in oncology.Nature biomedical engineering · 2022Review
- A time-based single transmission-line readout with position multiplexing.Biomedical engineering letters · 2022Article
- Sub-2 mm depth of interaction localization in PET detectors with prismatoid light guide arrays and single-ended readout using convolutional neural networks.Medical physics · 2021Article
- Development and initial characterization of a high-resolution PET detector module with DOI.Biomedical physics & engineering express · 2020Article
- Prismatoid light guide array for enhanced gamma ray localization in PET: a Monte Carlo simulation study of scintillation photon transport.Physics in medicine and biology · 2020Article
- Depth-of-interaction study of a dual-readout detector based on TOFPET2 application-specific integrated circuit.Physics in medicine and biology · 2019Article
- A second-generation virtual-pinhole PET device for enhancing contrast recovery and improving lesion detectability of a whole-body PET/CT scanner.Medical physics · 2019Article
- Innovations in Instrumentation for Positron Emission Tomography.Seminars in nuclear medicine · 2018Review
- Development and Evaluation of mini-EXPLORER: A Long Axial Field-of-View PET Scanner for Nonhuman Primate Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018Article
- Feasibility of Using Crystal Geometry for a DOI Scintillation Detector.IEEE transactions on radiation and plasma medical sciences · 2018Article
- Depth of interaction determination in monolithic scintillator with double side SiPM readout.EJNMMI physics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeIn support of a project to build a total-body PET scanner with an axial field-of-view of 2 m, the authors are developing simple, cost-effective block detectors with combined time-of-flight (TOF) and depth-of-interaction (DOI) capabilities.
methodsThis work focuses on investigating the potential of phosphor-coated crystals with conventional PMT-based block detector readout to provide DOI information while preserving timing resolution. The authors explored a variety of phosphor-coating configurations with single crystals and crystal arrays. Several pulse shape discrimination techniques were investigated, including decay time, delayed charge integration (DCI), and average signal shapes.
resultsPulse shape discrimination based on DCI provided the lowest DOI positioning error: 2 mm DOI positioning error was obtained with single phosphor-coated crystals while 3-3.5 mm DOI error was measured with the block detector module. Minimal timing resolution degradation was observed with single phosphor-coated crystals compared to uncoated crystals, and a timing resolution of 442 ps was obtained with phosphor-coated crystals in the block detector compared to 404 ps without phosphor coating. Flood maps showed a slight degradation in crystal resolvability with phosphor-coated crystals; however, all crystals could be resolved. Energy resolution was degraded by 3%-7% with phosphor-coated crystals compared to uncoated crystals.
conclusionsThese results demonstrate the feasibility of obtaining TOF-DOI capabilities with simple block detector readout using phosphor-coated crystals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.