Evidence map›Paper›PMID 26843112›Full record

SynthesisMolecular neurobiology2017

Endovascular Treatment Versus Intravenous Thrombolysis for Acute Ischemic Stroke: a Quantitative Review and Meta-Analysis of 21 Randomized Trials.

Chen-Chen Tan, Hui-Fu Wang, Jin-Long Ji, Meng-Shan Tan, Lan Tan, Jin-Tai Yu

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The progress of telestroke in China.Stroke and vascular neurology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Chen-Chen TanDepartment of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China.
Hui-Fu WangDepartment of Neurology, Nanjing Medical University, Nanjing, China.
Jin-Long JiDepartment of Cardiology, The Affiliated Cardiovascular Hospital of Qingdao University, Qingdao, China.
Meng-Shan TanDepartment of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China.
Lan TanDepartment of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Qingdao, China. dr.tanlan@163.com.
Jin-Tai YuDepartment of Neurology, University of California, San Francisco, USA. yu-jintai@163.com.
Qingdao Municipal Hospital · CNAffiliated Hospital of Qingdao University · CNNanjing Medical University · CNQingdao University · CNUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging studies suggest that endovascular treatment (EVT) may be superior to intravenous thrombolysis for acute ischemic stroke (AIS). We performed a systematic review and meta-analysis of all randomized controlled trials (RCTs) to assess the efficacy and safety of endovascular treatment in patients with acute ischemic stroke as compared with intravenous thrombolysis. We assessed RCTs investigating EVT versus intravenous thrombolysis (IVT) published up to June 2015. In total, 21 studies of 4473 patients were included in the systematic review and meta-analysis. EVT significantly improved functional outcome at 90 days (risk ratio (RR) 1.35, 95 % confidence interval (CI) 1.18 to 1.55, I

Indexed as

Administration, IntravenousBrain IschemiaEndovascular ProceduresFibrinolytic AgentsHumansRandomized Controlled Trials as TopicStrokeThrombolytic TherapyFibrinolytic AgentsAcute ischemic strokeEndovascular treatmentIntravenous thrombolysisMeta-analysisSystematic review

Identifiers

PMID26843112
OpenAlexW2301106449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.