ReviewCNS neuroscience & therapeutics2016
Effect of Acupuncture on the Motor and Nonmotor Symptoms in Parkinson's Disease--A Review of Clinical Studies.
Review in CNS neuroscience & therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Non-pharmacological therapies for treating non-motor symptoms in patients with Parkinson's disease: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2024Pooled it
- Efficacy and Safety of Electroacupuncture on Insomnia in Parkinson's Disease: A Multicentre, Randomized, Controlled Trial.Movement disorders clinical practice · 2025Trial
- Acupuncture and Sleep Quality Among Patients With Parkinson Disease: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Article
- Analysis of patellar reflex in Parkinson disease patients after an acupuncture treatment protocol - Case series study.Clinical parkinsonism & related disorders · 2025Article
- Electroacupuncture alleviates Parkinson's disease by inhibiting the NLRP3 inflammasome pathway.American journal of translational research · 2025Article
- Localization of brain networks activated by acupuncture at anatomically adjacent acupoints in healthy participants: neuroimaging evidence and implications for migraine and stroke.Frontiers in neuroscience · 2025Article
- Electroacupuncture alleviates Parkinson's disease by targeting HDAC/SIRT-mediated deacetylation of 14-3-3.Frontiers in aging neuroscience · 2025Article
- Acupuncture Effect on Reaction-Time Changes in Parkinson's Disease Patients-Case Study Series.Journal of clinical medicine · 2024Article
- Tongue Acupuncture to Treat Dysphagia in Patients with Parkinson's Disease: A Randomized Controlled Trial.Medical acupuncture · 2024Article
- Article
- Mapping knowledge domain of acupuncture for Parkinson's disease: a bibliometric and visual analysis.Frontiers in aging neuroscience · 2024Article
- Global trends and hotspots in research on acupuncture for neurodegenerative diseases over the last decade: a bibliometric and visualization analysis.Frontiers in aging neuroscience · 2024Review
- Potential role of acupuncture in the treatment of Parkinson's disease: A narrative review.Integrative medicine research · 2023Review
- Efficacy of acupuncture for the treatment of Parkinson's disease-related constipation (PDC): A randomized controlled trial.Frontiers in neuroscience · 2023Article
- Effectiveness of Acupuncture in Parkinson's Disease Symptoms-A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Acupuncture in the Treatment of Parkinson's Disease with Sleep Disorders and Dose Response.BioMed research international · 2022Article
- Low-Dimensional Dynamics of Brain Activity Associated with Manual Acupuncture in Healthy Subjects.Sensors (Basel, Switzerland) · 2021Article
- Effect of Acupuncture on Movement Function in Patients with Parkinson's Disease: Network Meta-Analysis of Randomized Controlled Trials.Healthcare (Basel, Switzerland) · 2021Article
- Investigation of Therapeutic Response Markers for Acupuncture in Parkinson's Disease: An Exploratory Pilot Study.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease is a neurodegenerative disorder. Parkinson's clinical feature is characterized by its motor manifestations, although its many nonmotor symptoms occur earlier and have more profound impact on the quality of patient's life. Acupuncture has been increasingly popular and has been used to treat patients with Parkinson's. In this article, we have studied the clinical reports of acupuncture treatment for Parkinson's, which were listed in Medline, PubMed, EMBASE, CNKI, and CINAHL databases in the past 15 years. It was found that acupuncture either manual or electroacupuncture stimulation at specific acupoints relieved some motor symptoms in patients with Parkinson's and markedly improved many nonmotor symptoms such as psychiatric disorders, sleep problems, and gastrointestinal symptoms. When it was used as an adjunct for levodopa, acupuncture improved therapeutic efficacy and reduced dosage and the occurrence of side effects of levodopa. However, the results were constrained by small sample sizes, methodological flaws, and blinding methods of studies. Although the evidence for the effectiveness of acupuncture for treating Parkinson's is inconclusive, therapeutic potential of acupuncture seems quite promising. More studies, either comparative effectiveness research or high-quality placebo-controlled clinical studies are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.