Evidence map›Paper›PMID 26842819›Full record

ArticleChromosoma2017

Discovery of the youngest sex chromosomes reveals first case of convergent co-option of ancestral autosomes in turtles.

E E Montiel, D Badenhorst, J Tamplin, R L Burke, N Valenzuela

Abstract read
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In one paragraph

Article in Chromosoma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  7. Sex-specific splicing of Z- and W-borneProceedings of the National Academy of Sciences of the United States of America · 2022
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  8. Review
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  11. Thermosensitive sex chromosome dosage compensation in ZZ/ZW softshell turtles,Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  12. The timing of genetic degeneration of sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

E E MontielDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA, 50011, USA.
D BadenhorstDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA, 50011, USA.
J TamplinDepartment of Biology, University of Northern Iowa, Cedar Falls, IA, USA.
R L BurkeDepartment of Biology, Hofstra University, Hempstead, NY, USA.
N ValenzuelaDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA, 50011, USA. nvalenzu@iastate.edu.
Iowa State University · USHofstra University · USUniversity of Northern Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most turtle species possess temperature-dependent sex determination (TSD), but genotypic sex determination (GSD) has evolved multiple times independently from the TSD ancestral condition. GSD in animals typically involves sex chromosomes, yet the sex chromosome system of only 9 out of 18 known GSD turtles has been characterized. Here, we combine comparative genome hybridization (CGH) and BAC clone fluorescent in situ hybridization (BAC FISH) to identify a macro-chromosome XX/XY system in the GSD wood turtle Glyptemys insculpta (GIN), the youngest known sex chromosomes in chelonians (8-20 My old). Comparative analyses show that GIN-X/Y is homologous to chromosome 4 of Chrysemys picta (CPI) painted turtles, chromosome 5 of Gallus gallus chicken, and thus to the X/Y sex chromosomes of Siebenrockiella crassicollis black marsh turtles. We tentatively assign the gene content of the mapped BACs from CPI chromosome 4 (CPI-4) to GIN-X/Y. Chromosomal rearrangements were detected in G. insculpta sex chromosome pair that co-localize with the male-specific region of GIN-Y and encompass a gene involved in sexual development (Wt1-a putative master gene in TSD turtles). Such inversions may have mediated the divergence of G. insculpta sex chromosome pair and facilitated GSD evolution in this turtle. Our results illuminate the structure, origin, and evolution of sex chromosomes in G. insculpta and reveal the first case of convergent co-option of an autosomal pair as sex chromosomes within chelonians.

Indexed as

Sex ChromosomesAnimalsComparative Genomic HybridizationFemaleIn Situ Hybridization, FluorescenceKaryotypeMaleTurtlesComparative genome and BAC in situ hybridization molecular cytogeneticsConvergent ancestral reconstructionEvolution of genome and sex chromosome organizationGenotypic and temperature-dependent sex determinationTurtle reptile vertebratesWt1 chromosomal rearrangement

Identifiers

PMID26842819
OpenAlexW2265600651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.