Evidence map›Paper›PMID 26842608›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2016

Detection of wall and neck calcification of unruptured intracranial aneurysms with flat-detector computed tomography.

Osman Kizilkilic, Eldeniz Huseynov, Sedat G Kandemirli, Naci Kocer, Civan Islak

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Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Osman KizilkilicDivision of Neuroradiology, Istanbul University, Turkey osmank@istanbul.edu.tr.
Eldeniz HuseynovDivision of Neuroradiology, Istanbul University, Turkey.
Sedat G KandemirliDivision of Neuroradiology, Istanbul University, Turkey.
Naci KocerDivision of Neuroradiology, Istanbul University, Turkey.
Civan IslakDivision of Neuroradiology, Istanbul University, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectMicrosurgical clipping is a widely used surgical technique in intracranial aneurysm treatment. It can be difficult in large sized aneurysms, and those with wide necks, thick walls and calcification located in the vicinity of the neck. This study reviewed calcification of the intracranial aneurysm wall and its relation to patient age, gender, location and size of the aneurysm. A possible cut-off value after which the aneurysm calcification rate increases was also investigated to classify patients' risk factors for microclipping.

methodsA retrospective review of all unruptured intracranial aneurysms that underwent digital subtraction angiography at a single centre was performed. Flat-detector computed tomography images of the aneurysm were reviewed for aneurysm location, size and calcification. The independent samples t test and χ(2) test were used to show the relation between aneurysm wall calcification and patient age, gender, aneurysm localisation and size.

resultsNone of the reviewed factors were statistically significantly related to aneurysm calcification except aneurysm size (P < 0.01). Receiver operating characteristic curves showed aneurysms greater than 10.5 mm could be predicted to be calcified with a sensitivity of 80% and specificity of 63%.

conclusionIn this study, the presence of calcification was related to aneurysm size. Larger aneurysms were more likely to be calcified. Aneurysms greater than 10.5 mm should be further investigated with a modality such as flat-detector computed tomography to show the calcification in detail, especially if microclipping is considered.

Indexed as

AdolescentAdultAgedAngiography, Digital SubtractionCalcinosisFemaleHumansIntracranial AneurysmMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSensitivity and SpecificityTomography, X-Ray Computedcalcificationflat-detector computed tomographyIntracranial aneurysm

Identifiers

PMID26842608
PMCPMC4984361

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.