ArticleAfrican journal of primary health care & family medicine2015
Intestinal helminth infections amongst HIV-infected adults in Mthatha General Hospital, South Africa.
Article in African journal of primary health care & family medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2025Pooled it
- Prevalence of soil-transmitted helminth infections in HIV patients: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Prevalence and Associated Risk Factors of Human Intestinal Helminths Parasitic Infections in Ethiopia: A Systematic Review and Meta-Analysis.TheScientificWorldJournal · 2022Pooled it
- The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.PLoS neglected tropical diseases · 2019Pooled it
- Water-Energy-Food Security and Health in South Africa: A Scoping Review.JAMA network open · 2026Article
- A Review of Global Patterns in Gut Microbiota Composition, Health and Disease: Locating South Africa in the Conversation.Microorganisms · 2025Review
- Exploring Gene Expression Changes in Murine Female Genital Tract Tissues Following Single and Co-Infection withPathogens (Basel, Switzerland) · 2025Article
- Characterization of microRNA Expression Profiles of Murine Female Genital Tracts FollowingMicroorganisms · 2025Article
- HIV-Helminth Co-Infections and Immune Checkpoints: Implications for Cancer Risk in South Africa.Viruses · 2025Article
- Exploring microRNA-Mediated Immune Responses to Soil-Transmitted Helminth and Herpes Simplex Virus Type 2 Co-Infections.Diseases (Basel, Switzerland) · 2025Review
- Review
- Intervention to Prevent Recurrent Intestinal Parasitic Infections in People Living with HIV in Selected Parts of Eastern Cape, South Africa.Tropical medicine and infectious disease · 2024Article
- Telomere Length in a South African Population Co-Infected with HIV and Helminths.Current issues in molecular biology · 2024Article
- Herpes simplex virus type 2 in sub-Saharan Africa and the potential impact of helminth immune modulation.Frontiers in cellular and infection microbiology · 2024Review
- Prevalence of intestinal parasites in HIV/AIDS-infected patients with correlation to CD4+ T-cell count at hospital in Eastern India.Journal of family medicine and primary care · 2023Article
- Cytokine Gene Expression Profiles during HIV and Helminth Coinfection in Underprivileged Peri-Urban South African Adults.Diagnostics (Basel, Switzerland) · 2023Article
- Molecular investigation of Toxocara infection from the serum of people living with HIV in Alborz, Iran.BMC infectious diseases · 2023Article
- Review
- Demographic profile of HIV and helminth-coinfected adults in KwaZulu-Natal, South Africa.Southern African journal of infectious diseases · 2023Article
- Anaemia and Nutritional Status during HIV and Helminth Coinfection among Adults in South Africa.Nutrients · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn South Africa, studies on the prevalence of intestinal helminth co-infection amongst HIV-infected patients as well as possible interactions between these two infection sare limited.
aimTo investigate the prevalence of intestinal helminth infestation amongst adults living with HIV or AIDS at Mthatha General Hospital.
settingStudy participants were recruited at the outpatient department of Mthatha General Hospital, Mthatha, South Africa.
methodsThis cross-sectional study was conducted between October and December 2013 amongst consecutive consenting HIV-positive adult patients. Socio-demographic and clinical information were obtained using data collection forms and structured interviews. Stool samples were collected to investigate the presence of helminths whilst blood samples were obtained for the measurement of CD4+ T-cell count and viral load.
resultsData were obtained on 231 participants, with a mean age of 34.9 years, a mean CD4 count of 348 cells/μL and a mean viral load of 4.8 log10 copies/mL. Intestinal helminth prevalence was 24.7%, with Ascaris Lumbricoides (42.1%) the most prevalent identified species. Statistically significant association was found between CD4 count of less than 200 cells/ μLand helminth infection (p = 0.05). No statistically significant association was found between intestinal helminth infection and the mean CD4 count (p = 0.79) or the mean viral load (p = 0.98).
conclusionA high prevalence of intestinal helminth infections was observed amongst the study population. Therefore, screening and treatment of helminths should be considered as part of the management of HIV and AIDS in primary health care.
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