ArticleThe Plant cell2016
Time-Series Transcriptomics Reveals That AGAMOUS-LIKE22 Affects Primary Metabolism and Developmental Processes in Drought-Stressed Arabidopsis.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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63 citing papers in PubMed.
- MYB59 is Linked to Natural Variation of Water-Use Associated With Warmer Temperatures inPlant-environment interactions (Hoboken, N.J.) · 2026Article
- Gene body methylation buffers noise in gene expression in plants.Nucleic acids research · 2026Article
- Suppression of miR426 enhances photoprotection and chlorophyll stability via upregulation of ELIP2 in Arabidopsis thaliana.Molecular biology reports · 2026Article
- INTACT-based guard cell transcriptomes from a progressive drought time course reveal targets for modifying stomatal responses.The Plant cell · 2025Article
- High-resolution time-series transcriptomic and metabolomic profiling reveals the regulatory mechanism underlying salt tolerance in maize.Genome biology · 2025Article
- Unlocking gene regulatory networks for crop resilience and sustainable agriculture.Nature biotechnology · 2025Review
- Time-series transcriptome analysis reveals the cascade mechanism of biological processes following the perturbation of the MVA pathway in Salvia miltiorrhiza.Plant molecular biology · 2025Article
- BADDADAN: Mechanistic modelling of time-series gene module expression.Quantitative plant biology · 2025Article
- Salinity survival: molecular mechanisms and adaptive strategies in plants.Frontiers in plant science · 2025Review
- Article
- The Characterization of a Novel PrMADS11 Transcription Factor fromInternational journal of molecular sciences · 2024Article
- Photosynthetic and transcriptome responses to fluctuating light inPlant direct · 2023Article
- Allelic variation in transcription factor PtoWRKY68 contributes to drought tolerance in Populus.Plant physiology · 2023Article
- Salinity-Triggered Responses in Plant Apical Meristems for Developmental Plasticity.International journal of molecular sciences · 2023Review
- Highlight Induced Transcriptional Priming against a Subsequent Drought Stress inInternational journal of molecular sciences · 2023Article
- IiSVP of Isatis indigotica can reduce the size and repress the development of floral organs.Plant cell reports · 2023Article
- Candidate regulators of drought stress in tomato revealed by comparative transcriptomic and proteomic analyses.Frontiers in plant science · 2023Article
- Response of the organellar and nuclear (post)transcriptomes of Arabidopsis to drought.Frontiers in plant science · 2023Article
- Metabolomic and transcriptomic responses of Adiantum (Frontiers in genetics · 2023Article
- The Plant Metabolic Changes and the Physiological and Signaling Functions in the Responses to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2023Article
3 more citing papers are in PubMed but not listed here.
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29 authors.
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Abstract
In Arabidopsis thaliana, changes in metabolism and gene expression drive increased drought tolerance and initiate diverse drought avoidance and escape responses. To address regulatory processes that link these responses, we set out to identify genes that govern early responses to drought. To do this, a high-resolution time series transcriptomics data set was produced, coupled with detailed physiological and metabolic analyses of plants subjected to a slow transition from well-watered to drought conditions. A total of 1815 drought-responsive differentially expressed genes were identified. The early changes in gene expression coincided with a drop in carbon assimilation, and only in the late stages with an increase in foliar abscisic acid content. To identify gene regulatory networks (GRNs) mediating the transition between the early and late stages of drought, we used Bayesian network modeling of differentially expressed transcription factor (TF) genes. This approach identified AGAMOUS-LIKE22 (AGL22), as key hub gene in a TF GRN. It has previously been shown that AGL22 is involved in the transition from vegetative state to flowering but here we show that AGL22 expression influences steady state photosynthetic rates and lifetime water use. This suggests that AGL22 uniquely regulates a transcriptional network during drought stress, linking changes in primary metabolism and the initiation of stress responses.
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