ArticleScientific reports2016
Courtship Pheromone Use in a Model Urodele, the Mexican Axolotl (Ambystoma mexicanum).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Histological and Gene Expression Analyses of the Arm and Finger Macroglands of Two Hyloxalus Frogs (Dendrobatidae).Molecular ecology · 2025Article
- Establishing a New Research Axolotl Colony.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Functional Protein Composition in Femoral Glands of Sand Lizards (Molecules (Basel, Switzerland) · 2022Article
- Recurrent Co-Option and Recombination of Cytokine and Three Finger Proteins in Multiple Reproductive Tissues Throughout Salamander Evolution.Frontiers in cell and developmental biology · 2022Article
- Love bites: male frogs (Plectrohyla, Hylidae) use teeth scratching to deliver sodefrin precursor-like factors to females during amplexus.Frontiers in zoology · 2021Article
- Pheromone Gene Diversification and the Evolution of Courtship Glands in Plethodontid Salamanders.Journal of molecular evolution · 2021Article
- Pheromonal communication in urodelan amphibians.Cell and tissue research · 2021Review
- Structural and bio-functional assessment of the postaxillary gland inZoological letters · 2020Article
- Imorin: a sexual attractiveness pheromone in female red-bellied newts (Cynops pyrrhogaster).Scientific reports · 2017Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Sex pheromones have been shown to constitute a crucial aspect of salamander reproduction. Until now, courtship pheromones of Salamandridae and Plethodontidae have been intensively studied, but information on chemical communication in other urodelan families is essentially lacking. The axolotl (Ambystoma mexicanum, Ambystomatidae) has a courtship display that suggests a key role for chemical communication in the orchestration of its sexual behavior, but no sex pheromones have yet been characterized from this species. Here we combined whole transcriptome analyses of the male cloaca with proteomic analyses of water in which axolotls were allowed to court to show that male axolotls secrete multiple ca. 20 kDa glycosylated sodefrin precursor-like factor (SPF) proteins during courtship. In combination with phylogenetic analyses, our data show that the male cloaca essentially secretes a courtship-specific clade of SPF proteins that is orthologous to salamandrid courtship pheromones. In addition, we identified an SPF protein for which no orthologs have been described from other salamanders so far. Overall, our study advocates a central role for SPF proteins during the courtship display of axolotls and adds knowledge on pheromone use in a previously unexplored deep evolutionary branch of salamander evolution.
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