Evidence map›Paper›PMID 26842041›Full record

ArticleNature2016

Reproducibility: A tragedy of errors.

David B Allison, Andrew W Brown, Brandon J George, Kathryn A Kaiser

Abstract read
In one paragraph

Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Irreproducible research and a typology of replication efforts.Research integrity and peer review · 2026
    Review
  3. Article
  4. Article
  5. Unlocking the benefits of transparent and reusable science for climate risk management.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Why and How to Account for Sex and Gender in Brain and Behavioral Research.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  20. Inaccuracy in the Scientific Record and Open Postpublication Critique.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023
    Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David B AllisonDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Alabama, USA.
Andrew W BrownOffice of Energetics and the Nutrition Obesity Research Center, University of Alabama at Birmingham, Alabama, USA.
Brandon J GeorgeOffice of Energetics, University of Alabama at Birmingham, Alabama, USA.
Kathryn A KaiserOffice of Energetics and the Nutrition Obesity Research Center, University of Alabama at Birmingham, Alabama, USA.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Editorial PoliciesRetraction of Publication as TopicAccess to InformationHumansPeer Review, ResearchPeriodicals as TopicReproducibility of ResultsResearch Design

Identifiers

PMID26842041
PMCPMC4831566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.