ArticlePloS one2016
Open-Source Selective Laser Sintering (OpenSLS) of Nylon and Biocompatible Polycaprolactone.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 91 citations in OpenAlex.
- Topological Tracks Patterned via 3D Printing Vascularize Murine Organ-Scale Constructs.Cell biomaterials · 2026Article
- Understanding the Mechanisms of Chemotherapy-Related Cardiotoxicity Employing hiPSC-Derived Cardiomyocyte Models for Drug Screening and the Identification of Genetic and Epigenetic Variants.International journal of molecular sciences · 2025Review
- A facile one step route that introduces functionality to polymer powders for laser sintering.Nature communications · 2024Article
- Design and Behavior of Lightweight Flexible Structure with Spatial Pattern Reducing Contact Surface Fraction.Polymers · 2023Article
- 3D printing biocompatible materials with Multi Jet Fusion for bioreactor applications.International journal of bioprinting · 2023Article
- Bioprinting Methods for Fabricating In Vitro Tubular Blood Vessel Models.Cyborg and bionic systems (Washington, D.C.) · 2023Review
- Combining printing and nanoparticle assembly: Methodology and application of nanoparticle patterning.Innovation (Cambridge (Mass.)) · 2022Review
- Laser Sintering Approaches for Bone Tissue Engineering.Polymers · 2022Review
- The Thermal Properties of a Prototype Insulation with a Gyroid Structure-Optimization of the Structure of a Cellular Composite Made Using SLS Printing Technology.Materials (Basel, Switzerland) · 2022Article
- Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Analysis and Optimization of Mechanical Properties of Laser-Sintered Cellulose/PLA Mixture.Materials (Basel, Switzerland) · 2021Article
- 3D Printing Polymer-based Bolus Used for Radiotherapy.International journal of bioprinting · 2021Review
- The Thermal Conductivity of 3D Printed Plastic Insulation Materials-The Effect of Optimizing the Regular Structure of Closures.Materials (Basel, Switzerland) · 2020Article
- Article
- Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates.Nature biomedical engineering · 2020Article
- Review
- Review
- Multiscale bioprinting of vascularized models.Biomaterials · 2019Review
- Polymeric 3D Printed Structures for Soft-Tissue Engineering.Journal of applied polymer science · 2018Article
- 3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments.Disease models & mechanisms · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selective Laser Sintering (SLS) is an additive manufacturing process that uses a laser to fuse powdered starting materials into solid 3D structures. Despite the potential for fabrication of complex, high-resolution structures with SLS using diverse starting materials (including biomaterials), prohibitive costs of commercial SLS systems have hindered the wide adoption of this technology in the scientific community. Here, we developed a low-cost, open-source SLS system (OpenSLS) and demonstrated its capacity to fabricate structures in nylon with sub-millimeter features and overhanging regions. Subsequently, we demonstrated fabrication of polycaprolactone (PCL) into macroporous structures such as a diamond lattice. Widespread interest in using PCL for bone tissue engineering suggests that PCL lattices are relevant model scaffold geometries for engineering bone. SLS of materials with large powder grain size (~500 μm) leads to part surfaces with high roughness, so we further introduced a simple vapor-smoothing technique to reduce the surface roughness of sintered PCL structures which further improves their elastic modulus and yield stress. Vapor-smoothed PCL can also be used for sacrificial templating of perfusable fluidic networks within orthogonal materials such as poly(dimethylsiloxane) silicone. Finally, we demonstrated that human mesenchymal stem cells were able to adhere, survive, and differentiate down an osteogenic lineage on sintered and smoothed PCL surfaces, suggesting that OpenSLS has the potential to produce PCL scaffolds useful for cell studies. OpenSLS provides the scientific community with an accessible platform for the study of laser sintering and the fabrication of complex geometries in diverse materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.